A Case Report of Gastric Adenocarcinoma with Adenosquamous Cell Carcinoma in Metastatic Lymph Nodes

• Published in: Nippon Shokaki Geka Gakkai zasshi Vol. 36; no. 10; pp. 1406 - 1409
• Main Authors: Shinohara, Tatsuo, Matsuzaki, Yasunori, Enomoto, Yusuke, Kawano, Fumiaki, Nakahira, Takaaki, Nakamura, Kunihide, Onitsuka, Toshio, Nakashima, Ken, Sekiya, Ryo
• Format: Journal Article
• Language: Japanese
• Published: The Japanese Society of Gastroenterological Surgery 2003
• Subjects: adenosquamous cell carcinoma in metastatic lymph nodes; gastric adenocarcinoma; squamous metaplasia of the adenocarcinoma
• ISSN: 0386-9768; 1348-9372
• DOI: 10.5833/jjgs.36.1406

We reported a case of gastric adenocarcinoma with metastatic lymph nodes showing adenosquamous cell carcinoma. A 76-year-old woman with an abnormality in gastroscopy and admitted to our hospital was found to have a 0-IIc lesion on the posterior wall of the middle body and biopsy showed adenocarcinoma. We con-ducted total gastrectomy combined with distal pancreatectomy and splenectomy and Roux-en Y reconstruc-tion anastomosis. The pancreatic body was excised for lymph node invasion on the lesser curvature. Macro-scopic findings showed 0-IIc cancer measuring 4.0×2.5 cm on the posterior wall of the middle body and swol-len lymph nodes. Histologically, the lesion was diagnosed as poorly differentiated adenocarcinoma with signet ring cells and invasion limited to the submucosa. Microscopic findings of metastatic lymph nodes showed adenosquamous cell carcinoma-a very rare occurrence supporting the hypothesis that the majority of adenosquamous cell carcionoma probably arises from squamous metaplasia of adenocarcinoma.