Transplant Trial Watch

The study was adequately randomised and, understandably, clinicians could not be blinded to the group allocation, the comparator being standard cold storage on ice. [...]there was a significantly higher proportion of DCD livers transplanted from the OCS group than the cold storage group (51% versus...

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Bibliographic Details
Published inTransplant international Vol. 35; p. 10513
Main Author O’Callaghan, John M.
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media SA 16.05.2022
Frontiers Media S.A
Subjects
Cold storage
Conflicts of interest
Cryopreservation
Cytomegalovirus
Data analysis
Disease prevention
Health Archive
Humans
Ischemia
Liver transplants
Patients
Transplants
United States > US
everolimus
machine perfusion
CMV infection
liver transplantation
kidney transplantation
Online AccessGet full text
ISSN1432-2277
0934-0874
1432-2277
DOI10.3389/ti.2022.10513

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Summary:The study was adequately randomised and, understandably, clinicians could not be blinded to the group allocation, the comparator being standard cold storage on ice. [...]there was a significantly higher proportion of DCD livers transplanted from the OCS group than the cold storage group (51% versus 26%). There were 298 patients included in the modified intention to treat analysis, which showed a significant decrease in EAD when the OCS machine was used compared to standard cold storage. There was a significantly higher proportion of DCD livers transplanted from the machine perfusion group than the cold storage group (51% versus 26%).
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ISSN:1432-2277
0934-0874
1432-2277
DOI:10.3389/ti.2022.10513