Polyethyleneimine incorporated hydroxyapatite for improved colloidal stability

• Published in: Bulletin of the Korean Chemical Society Vol. 45; no. 7; pp. 614 - 619
• Main Authors: Choi, Hyebin, An, Jaun, Lee, Keunyoung, Kwon, Ki‐Young
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley‐VCH Verlag GmbH & Co. KGaA 01.07.2024; 대한화학회
• Subjects: amine; hydroxyapatite; PEI; surface modification; 화학
• ISSN: 1229-5949; 0253-2964; 1229-5949
• DOI: 10.1002/bkcs.12855

We report on the preparation of a polyethyleneimine‐incorporated hydroxyapatite (PEI‐HAP) and its enhanced colloidal stability. Three PEI‐HAPs having different amine contents are synthesized by hydrothermal treatment (200 °C) of the HAP prepared at room temperature (rt‐HAP). The crystallinity of PEI‐HAP is improved compared to rt‐HAP due to the heat treatment. In addition, the size of PEI‐HAP (50.4 nm) increased compared to rt‐HAP (32.1 nm) after heat treatment. However, the presence (or concentration) of PEI has little effect on the crystallinity and size of the samples. Ninhydrin test indicates the presence of amine group in PEI‐HAPs. XPS experiments verified that maximum amine content amounts to 2.81%. As the amount of amine increases, the zeta potential is changed from −22.6 to +31.7 mV due to the adsorption of PEI on HAP surface. Consequently, the sample having high positive valuable zeta potential of +31.7 mV exhibits colloidal stability of more than 6 h. The PEI incorporated hydroxyapatite (PEI‐HAP) was prepared by hydrothermal synthesis at 200 °C using a mixture of HAP synthesized at room temperature and PEI solutions. As the amount of PEI increases, zeta potential value become more positive and the colloidal stability of the sample improved. It was attributed to the presence of amines on the surface of HAP preventing the aggregation of HAP.