Clinical study on acupuncture in treating diarrhea-predominant irritable bowel syndrome

• Published in: Journal of acupuncture and tuina science Vol. 6; no. 6; pp. 360 - 362
• Main Authors: Liu, Hui-rong, Yang, Yun, Wu, Huan-gan
• Format: Journal Article
• Language: English
• Published: Heidelberg Shanghai Research Institute of Acupuncture and Meridian 01.12.2008; Springer Nature B.V
• Subjects: Acupuncture; Clinical Study; Irritable bowel syndrome; Medicine; Medicine & Public Health; R246.1; Serotonin; 五羟色胺; Irritable Bowel Syndrome; 血清素; Indirect Moxibustion; 针灸疗法; 间接灸; 肠易激综合征; Acupuncture-Moxibustion Therapy; 5-HT
• ISSN: 1672-3597; 1993-0399
• DOI: 10.1007/s11726-008-0360-1

Objective To observe the changes of 5-hydroxytryptamine (5-HT) in colonic membrane of diarrhea-predominant irritable bowel syndrome (IBS-D) and the clinical efficacy of herbal cake-partitioned moxibustion in treating it, and to explore the action mechanisms. Methods Seventy-three subjects were randomized into two groups: moxibustion group in which 37 cases were treated by herbal cake-partitioned moxibustion and needling group in which 36 cases were treated by needling. The clinical efficacy and 5-HT expression in colonic membrane were observed. Results The cure rate was 43.2% in the moxibustion group and 36.1% in the needling group, with no significant difference between the two groups ( P >0.05). Herbal cake-partitioned moxibustion could reduce 5-HT expression in colonic membrane. Conclusion Herbal cake-partitioned moxibustion might improve the clinical symptoms of IBS-D by reducing 5-HT expression.