Reliability of 4D Flow MRI for Investigation of Fetal Cardiovascular Hemodynamics in the Third Trimester

Four-dimensional flow MRI was feasible in third-trimester fetuses, and hemodynamic measurements were precise across measurement locations, internally consistent based on conservation of mass, repeatable from test-retest data, and correlated to two-dimensional phase contrast MRI measurements.

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Bibliographic Details
Published in	Radiology. Cardiothoracic imaging Vol. 6; no. 6; p. e240119
Main Authors	Englund, Erin K., Fujiwara, Takashi, Smith, Sarah A., Meyers, Mariana L., Friesen, Richard M., Browne, Lorna P., Barker, Alex J.
Format	Journal Article
Language	English
Published	United States Radiological Society of North America 01.12.2024
Subjects	Adult Aortic Coarctation - diagnostic imaging Aortic Coarctation - embryology Blood Circulation - physiology Echocardiography, Doppler - methods Echocardiography, Doppler - statistics & numerical data Echocardiography, Four-Dimensional - methods Echocardiography, Four-Dimensional - statistics & numerical data Female Fetal Heart - diagnostic imaging Fetal Heart - embryology Fetal Heart - physiology Gestational Age Hemodynamics - physiology Humans Magnetic Resonance Imaging - methods Magnetic Resonance Imaging - statistics & numerical data Pregnancy Trimester, Third Prospective Studies Reference Values Reproducibility of Results Technical Development Ultrasonography, Prenatal - methods Ultrasonography, Prenatal - statistics & numerical data Aorta Fetal MRI Hemodynamics/Flow Dynamics Cardiac Pulmonary Arteries
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ISSN	2638-6135 2638-6135
DOI	10.1148/ryct.240119

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Summary:	Four-dimensional flow MRI was feasible in third-trimester fetuses, and hemodynamic measurements were precise across measurement locations, internally consistent based on conservation of mass, repeatable from test-retest data, and correlated to two-dimensional phase contrast MRI measurements.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3 Author contributions: Guarantors of integrity of entire study, E.K.E., A.J.B.; study concepts/study design or data acquisition or data analysis/interpretation, all authors; manuscript drafting or manuscript revision for important intellectual content, all authors; approval of final version of submitted manuscript, all authors; agrees to ensure any questions related to the work are appropriately resolved, all authors; literature research, E.K.E., M.L.M., R.M.F., A.J.B.; clinical studies, all authors; experimental studies, E.K.E., S.A.S., A.J.B.; statistical analysis, E.K.E.; and manuscript editing, all authors
ISSN:	2638-6135 2638-6135
DOI:	10.1148/ryct.240119