Development of Acetylcysteine Jelly for the Prevention of Radiocontrast-induced Reductions in Renal Function and its Evaluation

Acetylcysteine is used for the prevention of radiocontrast-induced reductions in renal function. However, as an oral solution, acetylcysteine has an unpleasant taste and smell, which can cause discomfort to patients. To solve this problem, we prepared an oral jelly of acetylcysteine consisting of ac...

Full description

Saved in:
Bibliographic Details
Published inIryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) Vol. 31; no. 5; pp. 355 - 359
Main Authors Kiyokawa, Masami, Shinzato, Rika, Sugawara, Mitsuru, Suda, Noriyuki, Kaneuchi, Miki, Miyazaki, Katsumi, Kohri, Naonori
Format Journal Article
LanguageJapanese
Published Japanese Society of Pharmaceutical Health Care and Sciences 2005
Subjects
acetylcysteine
in-hospital preparation
jelly
radiocontrast
Online AccessGet full text
ISSN1346-342X
1882-1499
1882-1499
DOI10.5649/jjphcs.31.355

Cover

More Information
Summary:Acetylcysteine is used for the prevention of radiocontrast-induced reductions in renal function. However, as an oral solution, acetylcysteine has an unpleasant taste and smell, which can cause discomfort to patients. To solve this problem, we prepared an oral jelly of acetylcysteine consisting of acetylcysteine, gelatin, flavoring agent and purified water. The unpleasant taste and smell of acetylcysteine were greatly reduced through the use of flavoring agents like apple. We expect our acetylcysteine jelly to be a highly effective preparation for the prevention of radiocontrast-induced reductions in renal function.
ISSN:1346-342X
1882-1499
1882-1499
DOI:10.5649/jjphcs.31.355