Clinical Effect of LA-1 Gargle in Periodontal Disease

• Published in: Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) Vol. 33; no. 3; pp. 710 - 726
• Main Authors: KAMOI, Kyuichi, HARA, Yoshinari, HAYASE, Kazuo, DEGUCHI, Shinji, HORI, Toshio, MIYATA, Hiroyuki, MURAI, Seidai, INOBE, Tetsuya, MUKAI, Hiroshi, NAGATA, Tatsuya, ENDO, Katsunori, OGAWA, Yuuji
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY OF PERIODONTOLOGY 1991
• Subjects: Acessre04; Chemical plaque control; Gargle type; Periodontal disease
• ISSN: 0385-0110; 1880-408X; 1880-408X
• DOI: 10.2329/perio.33.710

Clinical investigations were conducted on the effect on periodontal disease of LA-1 gargle, prescribed the same as Acess, a paste used to treat gingivitis and marginal periodontitis, containing as principal components three kinds of medicinal herbs. The subjects consisted of 96 patients diagnosed with gingivitis or marginal periodontitis on the basis of clinical findings and other examinations. Each patient brushed his teeth without dentifrice the same way as before, and after that was given LA-1 gargle every morning and evening for 4 weeks. The results were as follows. 1. Inflammation in ingivitis was improved, and the efficacy rate of this agent was 92.3%. 2. Inflammation in marginal periodontitis was improved, and the effdcacy rate of this agent was 55.7% as of 2 weeks and 77.1% as of 4 weeks. 3. No side effects which seemed to be attributable LA-1 occurred during the period of the experiment. 4. An effect of LA-1 on periodontal disease was demonstrated. LA-1 is considered to be an effective agent as a proprietary drug.