Primary Yolk Sac Tumors of the Mesentery: A Report of Two Cases

Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscop...

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Published inAmerican journal of clinical pathology Vol. 101; no. 1; pp. 42 - 47
Main Authors Jones, Michael A., Clement, Philip B., Young, Robert H.
Format Journal Article
LanguageEnglish
Published Chicago, IL American Society of Clinical Pathologists 01.01.1994
Subjects
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ISSN0002-9173
1943-7722
DOI10.1093/ajcp/101.1.42

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Abstract Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscopically, both neoplasms exhibited several of the typical patterns of yolk sac tumor and stained immunohistochemically for alpha-fetoprotein. Both patients received chemotherapy postoperatively and are alive, but follow-up is short. The subject of extragonadal yolk sac tumors is reviewed, and histogenetic implications of their occasional origin in the mesentery is discussed.
AbstractList Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscopically, both neoplasms exhibited several of the typical patterns of yolk sac tumor and stained immunohistochemically for alpha-fetoprotein. Both patients received chemotherapy postoperatively and are alive, but follow-up is short. The subject of extragonadal yolk sac tumors is reviewed, and histogenetic implications of their occasional origin in the mesentery is discussed.
Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscopically, both neoplasms exhibited several of the typical patterns of yolk sac tumor and stained immunohistochemically for alpha-fetoprotein. Both patients received chemotherapy postoperatively and are alive, but follow-up is short. The subject of extragonadal yolk sac tumors is reviewed, and histogenetic implications of their occasional origin in the mesentery is discussed.Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscopically, both neoplasms exhibited several of the typical patterns of yolk sac tumor and stained immunohistochemically for alpha-fetoprotein. Both patients received chemotherapy postoperatively and are alive, but follow-up is short. The subject of extragonadal yolk sac tumors is reviewed, and histogenetic implications of their occasional origin in the mesentery is discussed.
Author Jones, Michael A.
Clement, Philip B.
Young, Robert H.
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Keywords Human
Immunohistochemistry
Etiopathogenesis
Mesentery
Genital diseases
Case study
Germ cell tumor
Pathology
Endodermal sinus tumor
Extragenital
Abdominal disease
Digestive diseases
Diagnosis
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Snippet Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are...
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StartPage 42
SubjectTerms Abdomen
Adolescent
alpha-Fetoproteins - analysis
Biological and medical sciences
Child, Preschool
Endodermal Sinus Tumor - embryology
Endodermal Sinus Tumor - pathology
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Male
Medical sciences
Mesentery - pathology
Peritoneal Neoplasms - embryology
Peritoneal Neoplasms - pathology
Tumors
Title Primary Yolk Sac Tumors of the Mesentery: A Report of Two Cases
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