Primary Yolk Sac Tumors of the Mesentery: A Report of Two Cases

• Published in: American journal of clinical pathology Vol. 101; no. 1; pp. 42 - 47
• Main Authors: Jones, Michael A., Clement, Philip B., Young, Robert H.
• Format: Journal Article
• Language: English
• Published: Chicago, IL American Society of Clinical Pathologists 01.01.1994
• Subjects: Abdomen; Adolescent; alpha-Fetoproteins - analysis; Biological and medical sciences; Child, Preschool; Endodermal Sinus Tumor - embryology; Endodermal Sinus Tumor - pathology; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Male; Medical sciences; Mesentery - pathology; Peritoneal Neoplasms - embryology; Peritoneal Neoplasms - pathology; Tumors; Human; Immunohistochemistry; Etiopathogenesis; Mesentery; Genital diseases; Case study; Germ cell tumor; Pathology; Endodermal sinus tumor; Extragenital; Abdominal disease; Digestive diseases; Diagnosis
• ISSN: 0002-9173; 1943-7722
• DOI: 10.1093/ajcp/101.1.42

Two yolk sac tumors that arose in the mesentery of the jejunum and the mesentery of the transverse colon of two male patients, aged 2 and 17 years, are reported. Both patients had abdominal masses. The tumors measured 9 and 11 cm in maximum dimension. One of them grew into the bowel lumen. Microscopically, both neoplasms exhibited several of the typical patterns of yolk sac tumor and stained immunohistochemically for alpha-fetoprotein. Both patients received chemotherapy postoperatively and are alive, but follow-up is short. The subject of extragonadal yolk sac tumors is reviewed, and histogenetic implications of their occasional origin in the mesentery is discussed.