Early TIPS in patients with cirrhosis and variceal bleeding

Despite steady improvement in survival after variceal bleeding in patients with cirrhosis, bleeding-related mortality remains high. Current treatment recommendations utilize a step-up strategy, in which only patients who rebleed despite drug and endoscopic therapy undergo TIPS (transjugular intrahep...

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Bibliographic Details
Published inNature reviews. Gastroenterology & hepatology Vol. 7; no. 10; pp. 536 - 538
Main Author Rossle, Martin
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.10.2010
Nature Publishing Group
Subjects
692/699/1503/1607/1604
692/699/1503/197
692/700/565/545
Biomedicine
Blood clot
Care and treatment
Complications and side effects
Gastroenterology
Germany
Hepatology
Liver cirrhosis
Medicine
Medicine & Public Health
Methods
Mortality
news-and-views
Prevention
Risk factors
Thrombosis
Germany
Online AccessGet full text
ISSN1759-5045
1759-5053
DOI10.1038/nrgastro.2010.147

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Summary:Despite steady improvement in survival after variceal bleeding in patients with cirrhosis, bleeding-related mortality remains high. Current treatment recommendations utilize a step-up strategy, in which only patients who rebleed despite drug and endoscopic therapy undergo TIPS (transjugular intrahepatic portosystemic shunt) implantation; however, in patients who are at high risk of rebleeding, early use of TIPS might greatly reduce mortality.
ISSN:1759-5045
1759-5053
DOI:10.1038/nrgastro.2010.147