A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

Abstract An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3- d ]pyrimidin-4(3 H )-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2 H -thieno[2,3- d ][1,3]oxazine-2,4(1 H )-diones, aro...

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Bibliographic Details
Published in	SynOpen (2017) Vol. 2; no. 2; pp. 0207 - 0212
Main Authors	Liu, Feize, Hou, Xueling, Nie, Li Fei, Bozorov, Khurshed, Decker, Michael, Huang, Guozheng
Format	Journal Article
Language	English
Published	Stuttgart · New York Georg Thieme Verlag 01.04.2018 Georg Thieme Verlag KG
Subjects	intramolecular cyclization letter one-pot synthesis pyrimidinone quinazolinone thieno[2,3-d]pyrimidin-4(3h)-one quinazolinone pyrimidinone pyrimidin-4(3H)-one intramolecular cyclization one-pot synthesis thieno[2,3
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ISSN	2509-9396 2509-9396
DOI	10.1055/s-0037-1610157

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Summary:	Abstract An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3- d ]pyrimidin-4(3 H )-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2 H -thieno[2,3- d ][1,3]oxazine-2,4(1 H )-diones, aromatic aldehydes, and amines.
ISSN:	2509-9396 2509-9396
DOI:	10.1055/s-0037-1610157