Acute pericarditis and cardiac tamponade: Bridging the gap between diagnosis and management

• Published in: Srpski arhiv za celokupno lekarstvo Vol. 153; no. 5-6; pp. 310 - 314
• Main Authors: Simeunovic, Dejan, Juricic, Stefan, Gataric, Nina, Ristic, Marko, Simeunovic, Filip, Milinkovic, Ivan, Peric, Valerija, Lasica, Ratko, Ristic, Arsen
• Format: Journal Article
• Language: English
• Published: Serbian Medical Society 2025
• Subjects: acute pericarditis; cardiac tamponade; pericardiocentesis; pericarial effusion
• ISSN: 0370-8179; 2406-0895
• DOI: 10.2298/SARH240927037S

Acute pericarditis arises from an inflammatory process affecting the pericardial tissue, leading to the subsequent formation of pericardial effusion as part of the body's inflammatory response. Cardiac tamponade occurs when a significant volume of fluid accumulates within the pericardial cavity, resulting in increased intrapericardial pressure and impaired diastolic filling, ultimately obstructing blood flow into the heart. Notably, even a relatively small pericardial effusion can precipitate tamponade, depending on the rate of fluid accumulation and the compliance of the pericardium. Pericardiocentesis remains the preferred intervention for the emergent management of patients presenting with cardiac tamponade. This procedure is typically performed via a subxiphoid or apical approach, with the selection of the access site guided by the distribution of the effusion as visualized on imaging. The timely execution of pericardiocentesis during the acute phase of tamponade is of paramount importance; failure to perform the procedure promptly may result in cardiovascular collapse, cardiac arrest, and ultimately, a potentially fatal outcome.