Evaluation of Prophylactic Negative-Pressure Wound Therapy for Primary Closure Wounds after Surgery for Lower Gastrointestinal Perforation

Purpose: Surgical site infection (SSI) is a major postoperative complication. Prophylactic negative-pressure wound therapy (pNPWT) became covered by insurance in Japan in April 2022. The aim of this study is to evaluate the efficacy of pNPWT in postoperative wound management following surgery for lo...

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Published inNippon Shokaki Geka Gakkai zasshi Vol. 58; no. 5; pp. 259 - 266
Main Authors Takeuchi, Hiroshi, Yoshimura, Shuntaro, Tashiro, Jo, Ishikawa, Shintaro, Hayashi, Yoko, Takehara, Kotone, Kawasaki, Seiji, Kono, Yoshiharu, Sato, Kenta, Nagakubo, Genta, Daimon, Mitsuhiro, Mori, Kazuhiko
Format Journal Article
LanguageEnglish
Published The Japanese Society of Gastroenterological Surgery 01.05.2025
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ISSN0386-9768
1348-9372
DOI10.5833/jjgs.2024.0027

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Summary:Purpose: Surgical site infection (SSI) is a major postoperative complication. Prophylactic negative-pressure wound therapy (pNPWT) became covered by insurance in Japan in April 2022. The aim of this study is to evaluate the efficacy of pNPWT in postoperative wound management following surgery for lower gastrointestinal perforation. Materials and Methods: The subjects were 48 patients who underwent emergency open surgery for lower gastrointestinal perforation between April 2020 and December 2023. They were divided into pNPWT (n=14) and non-NPWT (n=34) groups, and perioperative outcomes were compared. Results: There were no significant differences in patient background and surgical factors, except for sex. The incidence of superficial SSI was significantly lower in the pNPWT group, but the frequency of deep SSI did not differ significantly. There was also no significant difference in duration of antibiotic administration, postoperative hospital stay, or infection-related healthcare resource utilization. Conclusion: pNPWT as a postoperative wound management strategy for lower gastrointestinal perforation significantly reduces the incidence of superficial SSI without increasing medical costs, suggesting its clinical usefulness.
ISSN:0386-9768
1348-9372
DOI:10.5833/jjgs.2024.0027