Effects of Aging on Serum Antibody Titers against Periodontopathic Bacteria

• Published in: Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) Vol. 32; no. 2; pp. 667 - 672
• Main Authors: NITTA, Hiroshi, ICHIMURA, Mami, WATANABE, Hisashi, ISHIKAWA, Isao
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY OF PERIODONTOLOGY 1990
• Subjects: Aging; ELISA; Periodontal disease; Periodontopathic bacteria; Serum antibody titer
• ISSN: 0385-0110; 1880-408X; 1880-408X
• DOI: 10.2329/perio.32.667

Elevated serum IgG antibody titers against several periodontopathic bacteria in periodontitis patients have been reported. The purpose of this study was to investigate the effects of aging on serum IgG titers against these bacteria. Serum IgG titers against 7 periodontopathic bacteria were measured in eleven subjects in their 20's, ten in their 40's, six in their 50's and six in their 60's, all with healthy periodontal tissues, by ELISA method. Concerning the result of titers against B. gingivalis, B. loescheii, E. corrodens and F. nucleatum, there were no significant differences between the four age groups. However titers in subjects in their 20's, against A. actinomycetemcomitans, B. intermedius and C. ochracea were higher than those in other generations. This suggests that aging has little effect on the elevation of antibody titers against some periodontopathic bacteria in periodontitis patients, and that such serum antibody titers in patients seem to reflect the periodontal status.