Experimental study of the analgesic effect of kaikyushokushou-to (TJS-022)

Although some doctors use kampo medicine clinically, it has not yet achieved general acceptance. This seems to be partly caused by the paucity of reports on the effects of kampo medicine as evaluated by basic research. We performed a comparative study of the analgesic effects of kaikyushokushou-to (...

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Bibliographic Details
Published inJapanese Journal of Oral and Maxillofacial Surgery Vol. 45; no. 2; pp. 116 - 118
Main Authors HORI, Shinsuke, Ko, Saiseki, OKUBO, Yasunori, IIZUKA, Tadahiko, BESSHO, Kazuhisa, KANEDA, Noriko
Format Journal Article
LanguageEnglish
Published Japanese Society of Oral and Maxillofacial Surgeons 1999
Subjects
acetic acid writhing method
analgesic activity
hot-platemethod
kaikyushokushou-to
Randall-Selitto method
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.45.116

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Summary:Although some doctors use kampo medicine clinically, it has not yet achieved general acceptance. This seems to be partly caused by the paucity of reports on the effects of kampo medicine as evaluated by basic research. We performed a comparative study of the analgesic effects of kaikyushokushou-to (300, 600, 1200mg/kg, per os), saline (negative control), and diclofenac sodium (poistive control) in mice. All doses of kaikyushokushou-to had an analgesic effect. These results suggest that kaikyushokushou-to can be used for analgesic purposes clinically.
ISSN:0021-5163
2186-1579
DOI:10.5794/jjoms.45.116