Effects of methyl-B12 on the inflammation induced by CdCl2 in the testis of rats

Effects of methyl-B12 on the inflammation induced by CdCl2 in the testis of rats, in which a remarkable increase of oxidative reaction was observed, were investigated. The results are summarized as follows: 1) Serum enzyme activities, i.e., Al-p, LDH, GOT, GPT, did not show any change by the premedi...

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Bibliographic Details
Published inEnsho Vol. 5; no. 1; pp. 45 - 50
Main Authors Tamura, Yasushi, Yoshida, Sho, Hirai, Aizan, Sajiki, Junko, Fukuda, Yoshio, Fukushima, Etsuko
Format Journal Article
LanguageJapanese
Published The Japanese Society of Inflammation and Regeneration 01.01.1985
Subjects
anti-inflammation
Ca contents
inflammation by CdCl2
methyl-B12
rat testis
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ISSN0389-4290
1884-4006
DOI10.2492/jsir1981.5.45

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Summary:Effects of methyl-B12 on the inflammation induced by CdCl2 in the testis of rats, in which a remarkable increase of oxidative reaction was observed, were investigated. The results are summarized as follows: 1) Serum enzyme activities, i.e., Al-p, LDH, GOT, GPT, did not show any change by the premedication of methyl-B12. 2) Hemorrhage, the damage of blood vessel epithelia and the migration of wondering cells in the testis were reduced markedly by the premedication of methyl-B12. 3) The increase of Ca contents in the rat testis induced by CdCl2 was also supressed significantly by the premedication of methyl-B12. These suggest that methyl-B12 has anti-inflammatory effect against the hemorrhagic inflammation in the testis of rat administered CdCl2.
ISSN:0389-4290
1884-4006
DOI:10.2492/jsir1981.5.45