Microarray expression analysis of epithelial ovarian cancer with distinct differentiation

To identify gene expression profiling in epithelial ovarian cancer and to explore its correlation with histopathology characterization and prognosis. Gene expression profiles were generated from 10 hu- man ovarian frozen tissue specimens using Agilent Human 1A microarrays. Strikingly, clear differen...

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Bibliographic Details
Published inJournal of Medical Colleges of PLA Vol. 22; no. 6; pp. 373 - 375
Main Author 李艳红 张伟 朱少君 尹国武 闫凯麟 赵宏喜
Format Journal Article
LanguageEnglish
Published Department of Obstetrics and Gynaecology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China%Department of Pathology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China 01.12.2007
Subjects
上皮组织
卵巢癌
微阵列表达分析
组织病理学
ovarian cancer
microarray
differentiation
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ISSN1000-1948
DOI10.1016/S1000-1948(08)60021-0

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Summary:To identify gene expression profiling in epithelial ovarian cancer and to explore its correlation with histopathology characterization and prognosis. Gene expression profiles were generated from 10 hu- man ovarian frozen tissue specimens using Agilent Human 1A microarrays. Strikingly, clear differences of gene expression patterns were observed in ovarian cancer as compared to normal tissues. Unique gene pro- files were observed in moderately and poorly differentiated epithelial ovarian cancer. It is concluded that different histopathology characterization likely exists extensive molecular heterogeneity.
Bibliography:ovarian cancer, microarray ; differentiation
R737.31
differentiation
ovarian cancer, microarray
31-1002/R
ISSN:1000-1948
DOI:10.1016/S1000-1948(08)60021-0