Clinical observation on the therapeutic effects of zhongyan-2 recipe in treating 29 HIV-infected and AIDS patients

• Published in: Journal of traditional Chinese medicine Vol. 22; no. 2; p. 93
• Main Authors: Wang, Jian, Yu, Zhimin, Li, Guoqin, Zhang, Yongxiang, Guan, Chongfen, Lu, Weibo
• Format: Journal Article
• Language: English
• Published: China 01.06.2002
• Subjects: Acquired Immunodeficiency Syndrome - drug therapy; Acquired Immunodeficiency Syndrome - immunology; Adult; CD4-CD8 Ratio; Drug Combinations; Drugs, Chinese Herbal - therapeutic use; Female; HIV Infections - drug therapy; HIV Infections - immunology; Humans; Male; Middle Aged; Neopterin - blood; Phytotherapy; Viral Load
• ISSN: 0255-2922

To investigate the efficacy of Zhongyan-2 Recipe (ZY-2), a recipe consisting of Chinese herbal medicine. Twenty-nine HIV-infected patients were treated with ZY-2 for 3 months as one treatment course; and viral load, immune function and symptoms-signs were determined before and after treatment. After treatment, the absolute values of CD4 were elevated in 8 cases, and lowered in 14 cases, 7 cases were not changed; the ratio of CD4/CD8 were elevated in 2 cases, lowered in 1 case, 16 of them were not changed obviously. The CD4 and CD4/CD8 ratio were elevated simultaneously in 2 cases. Neopterin lowered in 4 cases, elevated in 11 cases, and not changed in 1 case. Viral load (VL) was lowered in 6 cases, elevated in 8 cases and not changed in 2 cases. The total effective rate was 42.28% on the basis of comprehensive assessment of VL, immune function, body weight and symptoms-signs. ZY-2 is an effective Chinese recipe in treating HIV-infected patients.