Ménétrier's disease associated with ulcerative collitis

• Published in: Vojnosanitetski pregled Vol. 60; no. 6; pp. 747 - 751
• Main Authors: Mirkovic, Darko, Doder, Radoje, Ilic, Srbislav, Mitrovic, Miroslav, Ignjatovic, Mile
• Format: Journal Article
• Language: English
• Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2003
• Subjects: biopsy; colitis; diagnosis; differential; gastrectomy; gastritis; hypertrophic; ulcerative
• ISSN: 0042-8450; 2406-0720; 2406-0720
• DOI: 10.2298/VSP0306747M

In this paper a 21 year old patient was presented with M?n?trier's disease, associated with ulcerative colitis. The first symptoms of ulcerative colitis occured at the age of eleven, since when the patient has been conservatively treated several times because of the exacerbations of the desease. During control examinations presence of polipoid changes in stomach was discovered by upper endoscopy. Gastrectomy was suggested because the patient had excessive anemic syndrome which required weekly substitutional therapy with deplasmatic eritrocytes, as well as hypoproteinemia, while multiple polipoid changes suspect for malignancy were gastroscopically identifided. Patient accepted surgical treatment, and was transfered to the Clinic of Surgery. Total gastrectomy was performed, and patohystological finding confirmed M?n?trier's desease. After two weeks, the patient was released from the hospital in good general condition, with regular clinical and laboratory findings. U radu je prikazan bolesnik star 21 godinu kod koga je dijagnostikovana M?n?trierova bolest udruzena sa ulceroznim kolitisom. Prvi simptomi ulceroznog kolitisa javili su se u dobi od jedanaest godina otkada je u vise navrata lecen zbog egzacerbacije bolesti. Nakon kontrolnog ispitivanja ulceroznog kolitisa gornjom endoskopijom je utvrdjeno postojanje polipoidnih promena u zelucu. Posto je kod bolesnika bio prisutan izrazit anemijski sindrom koji je zahtevao supstitucionu terapiju deplazmatisanim eritrocitima prakticno svake nedelje, kao i hipoproteinemija, i zbog toga sto su prilikom gastroskopije uocene mnogobrojne polipoidne promene suspektne na malignu alteraciju bila je predlozena gastrektomija. Bolesnik je prihvatio ovaj vid lecenja, te je premesten u Hirusku kliniku radi operativnog lecenja. Uradjena je totalna gastrektomija, a patohistoloski nalaz ukazuje na M?n?trierovu bolest. Nakon dve nedelje bolesnik je otpusten iz Klinike u dobrom opstem stanju sa urednim klinicko-laboratorijskim nalazima.