The molecular form of IgM antibody to hepatitis B core antigen in sera from patients with hepatitis B virus infection

The molecular form of IgM antibody to hepatitis B core antigen (IgM anti-HBc) was analysed by high speed liqud chromatography and enzyme immunoassay (CORZYME-M) in 8 sera from 6 patients with acute hepatitis B virus infection and in 6 sera from 6 patients with chronic hepatitis B virus infection. Th...

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Published inKanzo Vol. 28; no. 11; pp. 1423 - 1427
Main Authors HIRANE, Toshimitsu, YOKOTA, Katsuji, SUGA, Mitsuo, KODAMA, Toshinori, AKAHONAI, Yoshikazu, YACHI, Akira
Format Journal Article
LanguageJapanese
Published The Japan Society of Hepatology 1987
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ISSN0451-4203
1881-3593
DOI10.2957/kanzo.28.1423

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Summary:The molecular form of IgM antibody to hepatitis B core antigen (IgM anti-HBc) was analysed by high speed liqud chromatography and enzyme immunoassay (CORZYME-M) in 8 sera from 6 patients with acute hepatitis B virus infection and in 6 sera from 6 patients with chronic hepatitis B virus infection. The IgM anti-HBc was detected in not only 19S IgM fractions but also 7S IgM fractions. The IgM anti-HBc of 19S IgM fractions, however, was more predominant than that of 7S IgM fractions in both patients with acute and chronic hepatitis B virus infection. The result suggests that the molecular form of IgM anti-HBc may not be useful for differentiating acute from chronic hepatitis B virus infection.
ISSN:0451-4203
1881-3593
DOI:10.2957/kanzo.28.1423