Prospects for the use of medicinal plants extracts (Mallotus oppositifolius and Kalanchoe crenata) as antimicrobials against salmonellosis in poultry

• Published in: Online journal of animal and feed research
• Main Authors: ASSANDI, Kouamé Rivière, TOURE, Alassane, BONNY, Aya Carole, KAROU, Tago Germain
• Format: Journal Article
• Language: English
• Published: 30.07.2024
• ISSN: 2228-7701; 2228-7701
• DOI: 10.51227/ojafr.2024.29

This study is a contribution to the search for alternatives to combat antibiotic resistance in Salmonella strains in poultry farming. The objective of this work is to highlight the main phytochemical compounds of 2 Ivorian medicinal plants (Mallotus oppositifolius and Kalanchoe crenata) and to evaluate their acute oral toxicity with a view to their use in the poultry sector, to fight against certain avian pathologies, including Salmonellosis. The phytochemical compounds of the different extracts of the plants used in this study were highlighted by colouring and precipitation methods. Acute oral toxicity was adapted to broilers according to the guideline OECD 425, 2008. This experimental study, which is the very first adapted to broiler chickens, was carried out with the agreement of the National Ethics Committee for Life and Health Sciences. The phytochemical screening carried out showed that each of these three antibacterial extracts possesses at least the major phytochemical groups sought. At the end of the acute oral toxicity study, no mortality was observed and the biochemical analysis of the subjects' blood showed creatinine values ​​≤ 10 mg/L.; aspartate aminotransferase (ASAT) ≤ 275 IU/L; alanine aminotransferase (ALT) ≤ 50 IU/L, urea=0.01g/L, CRP≤6 mg/L; and blood sugar was between 2 and 5 g/L in subjects from different batches. Ultimately, the aqueous and ethanolic extracts of Mallotus oppositifolius and the ethanolic extract of Kalanchoe crenata can be used as an antibacterial in broiler farming. This study is a contribution to the search for alternatives to combat antibiotic resistance in Salmonella strains in poultry farming. The objective of this work is to highlight the main phytochemical compounds of 2 Ivorian medicinal plants (Mallotus oppositifolius and Kalanchoe crenata) and to evaluate their acute oral toxicity with a view to their use in the poultry sector, to fight against certain avian pathologies, including Salmonellosis. The phytochemical compounds of the different extracts of the plants used in this study were highlighted by colouring and precipitation methods. Acute oral toxicity was adapted to broilers according to the guideline OECD 425, 2008. This experimental study, which is the very first adapted to broiler chickens, was carried out with the agreement of the National Ethics Committee for Life and Health Sciences. The phytochemical screening carried out showed that each of these three antibacterial extracts possesses at least the major phytochemical groups sought. At the end of the acute oral toxicity study, no mortality was observed and the biochemical analysis of the subjects' blood showed creatinine values ​​≤ 10 mg/L.; aspartate aminotransferase (ASAT) ≤ 275 IU/L; alanine aminotransferase (ALT) ≤ 50 IU/L, urea=0.01g/L, CRP≤6 mg/L; and blood sugar was between 2 and 5 g/L in subjects from different batches. Ultimately, the aqueous and ethanolic extracts of Mallotus oppositifolius and the ethanolic extract of Kalanchoe crenata can be used as an antibacterial in broiler farming.