Autologous Plasma Filler in Treatment of Nasolabial Folds

• Published in: QJM : An International Journal of Medicine Vol. 113; no. Supplement_1
• Main Authors: Abdelfattah, N S, Elhusseiny, R M, Mahmoud, A A
• Format: Journal Article
• Language: English
• Published: Oxford University Press 01.03.2020
• Subjects: Platelet rich plasma; Nasolabial folds; Platelet rich fibrin matrix
• ISSN: 1460-2725; 1460-2393
• DOI: 10.1093/qjmed/hcaa046.009

Abstract Background There is an increasing demand for aesthetic correction of deep NLFs. Dermal fillers are one of the nonsurgical options for soft tissue augmentation, plasma filler is a recent technique tried in soft tissue augmentation. This procedure could be performed on an outpatient basis at a moderate cost, without any rejection reactions. Objective The presented study aimed to confirm the efficacy and safety of autologous plasma filler in treating nasolabial fold wrinkles. Subjects and Methods The present study included 40 females attended the Dermatology outpatient clinic of Ain Shams University Hospitals from March 2017 to November 2017. The age of patients ranged from 20 to 60 years old, with the mean age of 38.60 years old ± 11.48 SD. Results The overall success of our study was defined according to clinical improvement of NLFs subjectively by patients' satisfaction score which showed that 42.5% of patients rated their improvement as excellent, 35% as good and 22.5% as poor. The mean of WSRS decreased significantly from (3.20 ± 0.96) before treatment to (1.50 ±0.630) after 4 weeks of the treatment session. Furthermore, the mean value of GAIS scores 2 weeks after treatment session was (4.47 + 0.730) then become (4.03±0.964) 4 weeks after the treatment session. Conclusion In conclusion, Treatment with plasma filler injection resulted in significant improvement of NLFs with minimal complications.