人附睾蛋白4在肺癌中的研究进展
人附睾蛋白4（human epididymis 4,HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床数据显示它与肺癌的诊断及预后有一定的相关性,因此可能成为临床上肺癌的诊断及预后评估的新指标。...
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| Published in | Zhongguo fei ai za zhi Vol. 18; no. 3; pp. 184 - 186 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese English |
| Published |
天津市和平区南京路228号300020
天津医科大学总医院肿瘤科, 天津,300052
20.03.2015
中国肺癌杂志编辑部 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1009-3419 1999-6187 |
| DOI | 10.3779/j.issn.1009-3419.2015.03.10 |
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| Abstract | 人附睾蛋白4（human epididymis 4,HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床数据显示它与肺癌的诊断及预后有一定的相关性,因此可能成为临床上肺癌的诊断及预后评估的新指标。 |
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| AbstractList | 人附睾蛋白4（human epididymis 4,HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床数据显示它与肺癌的诊断及预后有一定的相关性,因此可能成为临床上肺癌的诊断及预后评估的新指标。 人附睾蛋白4（human epididymis 4, HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族，具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达，现有临床数据显示它与肺癌的诊断及预后有一定的相关性，因此可能成为临床上肺癌的诊断及预后评估的新指标。 |
| Abstract_FL | Human epididymis 4 (HE4) belongs to whey acidic 4-disulfide center protein family. It has the char-acteristics of inhibiting trypsin and high expression in the serum or malignant pleural eusion of patients with lung cancer. Clinical data showed that it has certain relevance to the diagnosis and prognosis of lung cancer. HE4 may be a new indicator of clinical diagnosis and prognosis evaluation. |
| Author | 马晴 王倩 钟殿胜 |
| AuthorAffiliation | 天津医科大学总医院肿瘤科,天津300052 |
| AuthorAffiliation_xml | – name: 天津医科大学总医院肿瘤科, 天津,300052 – name: 300052 天津，天津医科大学总医院肿瘤科 Department of Medical Oncology, The General Hospital of Tianjin Medical University, Tianjin 300052, China |
| Author_FL | Qing MA Qian WANG Diansheng ZHONG |
| Author_FL_xml | – sequence: 1 fullname: Qing MA – sequence: 2 fullname: Qian WANG – sequence: 3 fullname: Diansheng ZHONG |
| Author_xml | – sequence: 1 fullname: 马晴 王倩 钟殿胜 |
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| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. 版权所有©《中国肺癌杂志》编辑部2015 Copyright ©2015 Chinese Journal of Lung Cancer. All rights reserved. 2015 |
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| DocumentTitleAlternate | Advances of Human Epididymis Protein 4 in Lung Cancer |
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| Keywords | Progress 进展 肺肿瘤 人附睾蛋白4 HE4 Lung neoplasms |
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| Notes | Human epididymis 4（HE4） belongs to whey acidic 4-disulfide center protein family. It has the characteristics of inhibiting trypsin and high expression in the serum or malignant pleural effusion of patients with lung cancer. Clinical data showed that it has certain relevance to the diagnosis and prognosis of lung cancer. HE4 may be a new indicator of clinical diagnosis and prognosis evaluation. HE4; Lung neoplasms; Progress Qing MA;Qian WANG;Diansheng ZHONG（Department of Medical Oncology, The General Hospital of Tianjin Medical University; Tianjin 300052 China） 12-1395/R |
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| Publisher | 天津医科大学总医院肿瘤科, 天津,300052 中国肺癌杂志编辑部 |
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| Snippet | 人附睾蛋白4（human epididymis 4,HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床... 人附睾蛋白4（human epididymis 4, HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族，具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达，现有临... |
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| SubjectTerms | Mini-Review 人附睾蛋白4 综述 肺肿瘤 进展 |
| Title | 人附睾蛋白4在肺癌中的研究进展 |
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