人附睾蛋白4在肺癌中的研究进展

人附睾蛋白4（human epididymis 4,HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床数据显示它与肺癌的诊断及预后有一定的相关性,因此可能成为临床上肺癌的诊断及预后评估的新指标。...

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Bibliographic Details
Published inZhongguo fei ai za zhi Vol. 18; no. 3; pp. 184 - 186
Main Author 马晴 王倩 钟殿胜
Format Journal Article
LanguageChinese
English
Published 天津市和平区南京路228号300020 天津医科大学总医院肿瘤科, 天津,300052 20.03.2015
中国肺癌杂志编辑部
Subjects
Mini-Review
人附睾蛋白4
综述
肺肿瘤
进展
Progress
进展
肺肿瘤
人附睾蛋白4
HE4
Lung neoplasms
Online AccessGet full text
ISSN1009-3419
1999-6187
DOI10.3779/j.issn.1009-3419.2015.03.10

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Summary:人附睾蛋白4（human epididymis 4,HE4）属于乳清酸性4-二硫化中心（WFDC）蛋白家族,具有胰蛋白酶抑制剂的特性。在肺癌患者血清中及恶性胸腔积患者胸水中呈高表达,现有临床数据显示它与肺癌的诊断及预后有一定的相关性,因此可能成为临床上肺癌的诊断及预后评估的新指标。
Bibliography:Human epididymis 4（HE4） belongs to whey acidic 4-disulfide center protein family. It has the characteristics of inhibiting trypsin and high expression in the serum or malignant pleural effusion of patients with lung cancer. Clinical data showed that it has certain relevance to the diagnosis and prognosis of lung cancer. HE4 may be a new indicator of clinical diagnosis and prognosis evaluation.
HE4; Lung neoplasms; Progress
Qing MA;Qian WANG;Diansheng ZHONG（Department of Medical Oncology, The General Hospital of Tianjin Medical University; Tianjin 300052 China）
12-1395/R
ISSN:1009-3419
1999-6187
DOI:10.3779/j.issn.1009-3419.2015.03.10