Extremely low birth weight and body size in early adulthood

• Published in: Archives of disease in childhood Vol. 89; no. 4; pp. 347 - 350
• Main Authors: Doyle, L W, Faber, B, Callanan, C, Ford, G W, Davis, N M
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01.04.2004; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD
• Subjects: Adolescent; Adult; Age; Biological and medical sciences; Birth weight; Birth weight, Low; BMI; Body Composition; Body Constitution - physiology; Body Height - physiology; Body Mass Index; Body size; Body Weight; Body Weight - physiology; Cerebral palsy; Child; Child, Preschool; Children & youth; Cohort Studies; confidence interval; Control Groups; Diseases of mother, fetus and pregnancy; ELBW; extremely low birth weight; General aspects; growth; Growth hormones; Gynecology. Andrology. Obstetrics; height; Humans; Infant; Infant, Newborn; Infant, Very Low Birth Weight - growth & development; Infants; Low birth weight; Medical sciences; NBW; normal birth weight; Original; Parents & parenting; Physical growth; Physiological aspects; Pregnancy. Fetus. Placenta; Puberty; standard deviation; Survivors; weight; Womens health; Young Children; Australia; Oceania; United States; Very low birthweight; Premature; Pediatrics; Newborn diseases; Pregnancy disorders; Prematurity; Body size; Early; Corporal biometry
• ISSN: 0003-9888; 1468-2044; 1468-2044
• DOI: 10.1136/adc.2002.025924

Aims: To determine the body size of extremely low birth weight (ELBW, birth weight 500–999 g) subjects in early adulthood. Methods: Cohort study examining the height and weight of 42 ELBW survivors free of cerebral palsy between birth and 20 years of age. Weight and height measurements were converted to Z (SD) scores. Results: At birth the subjects had weight Z scores substantially below zero (mean birth weight Z score −0.90, 95% CI −1.25 to −0.54), and had been lighter than average at ages 2, 5, and 8 years. However, by 14, and again at 20 years of age their weight Z scores were not significantly different from zero. At ages 2, 5, 8, 14, and 20 years of age their height Z scores were significantly below zero. Their height at 20 years of age was, however, consistent with their parents’ height. As a group they were relatively heavy for their height and their mean body mass index (BMI) Z score was almost significantly different from zero (mean difference 0.42, 95% CI −0.02 to 0.84). Their mean BMI (kg/m2) was 24.0 (SD 5.2); 14 had a BMI >25, and four had a BMI >30. Conclusions: Despite their early small size, by early adulthood the ELBW subjects had attained an average weight, and their height was consistent with their parents’ height. They were, however, relatively heavy for their height.