Comment on ‘Practical advice for avoidance of pain associated with insertion of intrauterine contraceptives’

With tolfenamic acid 200 mg three times a day started post-insertion, significantly reduced (p<0.01) spasmodic pain was reported in the subsequent 24 hours 4 ; and measured by visual analogue scales (VAS), there was significant post-insertion pain reduction at 10 minutes with mefenamic acid 500 m...

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Published inBMJ sexual & reproductive health Vol. 40; no. 2; pp. 150 - 151
Main Author Guillebaud, John
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 01.04.2014
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ISSN1471-1893
2515-1991
2045-2098
2515-2009
DOI10.1136/jfprhc-2014-100904

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Summary:With tolfenamic acid 200 mg three times a day started post-insertion, significantly reduced (p<0.01) spasmodic pain was reported in the subsequent 24 hours 4 ; and measured by visual analogue scales (VAS), there was significant post-insertion pain reduction at 10 minutes with mefenamic acid 500 mg given 60 minutes pre-insertion. 2 Moreover, the "absence of proof" from other good studies cited in the Cochrane Review 3 cannot be "proof of absence" of benefit by non-steroidal anti-inflammatory drugs (NSAIDS) for prostaglandin-related pain. Robinson et al. 5 reported in a double-blind randomised controlled trial that hysterosalpingography subjects receiving a 1% lidocaine cervical block totalling 6 ml had significantly less pain (p<0.001) measured by VAS from tenaculum placement, compared with a placebo intracervical saline injection group and a no-injection group.
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ObjectType-Correspondence-1
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ISSN:1471-1893
2515-1991
2045-2098
2515-2009
DOI:10.1136/jfprhc-2014-100904