Continuous Particle Trapping, Switching, and Sorting Utilizing a Combination of Dielectrophoresis and Alternating Current Electrothermal Flow

• Published in: Analytical chemistry (Washington) Vol. 91; no. 9; pp. 5729 - 5738
• Main Authors: Sun, Haizhen, Ren, Yukun, Hou, Likai, Tao, Ye, Liu, Weiyu, Jiang, Tianyi, Jiang, Hongyuan
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 07.05.2019
• Subjects: Activation; Alternating current; Analytical chemistry; Chemistry; colloids; Dielectrophoresis; Droplets; electric field; Electric fields; Electric potential; electric potential difference; Electrodes; filtration; Fluidics; geometry; Nanofluids; Particle sorting; Switching; Traffic control; Trapping; Voltage
• ISSN: 0003-2700; 1520-6882; 1520-6882
• DOI: 10.1021/acs.analchem.8b05861

We propose a simplified multifunctional traffic control approach that effectively combines dielectrophoresis (DEP) and alternating current electrothermal (ACET) flow to realize continuous particle trapping, switching, and sorting. In the designed microsystem, the combined DEP and ACET effects, which are symmetrically generated above a bipolar electrode surface, contribute to focus the incoming colloidal particles into a thin beam. Once the bipolar electrode is energized with an electric gate signal completely in phase with the driving alternating current (AC) signal, the spatial symmetry of the electric field can be artificially reordered by adjusting the gate voltage through field-effect traffic control. This results in a reshapable field stagnant region for precise switching of particles into the region of interest. Moreover, the integrated particle switching prior to the scaled particle trapping experiment is successfully conducted to demonstrate the feasibility of the combined strategy. Furthermore, a mixture of two types of particle sorting (i.e., density, size) with quick response performance is achieved by increasing the driving voltage with a maximum gate voltage offset, thus, extending the versatility of the designed device. Finally, droplet switching and filtration of the satellite droplets from the parent droplets is performed to successfully permit control of the droplet traffic. The proposed traffic control approach provides a promising technique for flexible manipulation of particulate samples and can be conveniently integrated with other micro/nanofluidic components into a complete functional on-chip platform owing to its simple geometric structure, easy operation, and multifunctionality.