Pharmacokinetics of Aztreonam in Healthy Subjects and Patients with Cystic Fibrosis and Evaluation of Dose-Exposure Relationships Using Monte Carlo Simulation

• Published in: Antimicrobial Agents and Chemotherapy Vol. 51; no. 9; pp. 3049 - 3055
• Main Authors: Vinks, Alexander A., van Rossem, Ronald N., Mathôt, Ron A. A., Heijerman, Harry G. M., Mouton, Johan W.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.09.2007
• Subjects: Adult; Algorithms; Anti-Bacterial Agents; Anti-Bacterial Agents - cerebrospinal fluid; Anti-Bacterial Agents - pharmacokinetics; Antibiotics. Antiinfectious agents. Antiparasitic agents; Aztreonam; Aztreonam - cerebrospinal fluid; Aztreonam - pharmacokinetics; Biological and medical sciences; Cystic Fibrosis; Cystic Fibrosis - metabolism; Dose-Response Relationship, Drug; Errors of metabolism; Female; Half-Life; Humans; Male; Medical sciences; Metabolic diseases; Miscellaneous hereditary metabolic disorders; Models, Statistical; Monte Carlo Method; Pharmacology; Pharmacology. Drug treatments; Pseudomonas aeruginosa; Human; Evaluation; Healthy subject; Respiratory disease; β-Lactams; Metabolic diseases; Cystic fibrosis; Exposure; Monobactam derivatives; Genetic disease; Antibiotic; Simulation; Azetidine derivatives; Aztreonam; Digestive diseases; Antibacterial agent; Pharmacokinetics; Dose; Pancreatic disease
• ISSN: 0066-4804; 1070-6283; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.01522-06

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC