Impact of Cethromycin (ABT-773) Therapy on Microbiological, Histologic, Immunologic, and Respiratory Indices in a Murine Model of Mycoplasma pneumoniae Lower Respiratory Infection

• Published in: Antimicrobial Agents and Chemotherapy Vol. 48; no. 8; pp. 2897 - 2904
• Main Authors: RIOS, Ana Maria, MEJIAS, Asuncion, HARDY, Robert Doug, CHAVEZ-BUENO, Susana, FONSECA-ATEN, Monica, KATZ, Kathy, HATFIELD, Jeanine, GOMEZ, Ana Maria, JAFRI, Hasan S, MCCRACKEN, George H, RAMILO, Octavio
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.08.2004
• Subjects: Airway Obstruction - etiology; Airway Obstruction - physiopathology; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Bronchial Hyperreactivity - etiology; Bronchial Hyperreactivity - physiopathology; Bronchoalveolar Lavage Fluid - chemistry; Bronchoalveolar Lavage Fluid - cytology; Cephalosporins; Cephalosporins - therapeutic use; Chemokines - metabolism; Cytokines - biosynthesis; Erythromycin; Erythromycin - analogs & derivatives; Erythromycin - therapeutic use; Experimental Therapeutics; Ketolides; Lung - immunology; Medical sciences; Mice; Mycoplasma pneumoniae; Pharmacology. Drug treatments; Plethysmography; Pneumonia, Mycoplasma; Pneumonia, Mycoplasma - drug therapy; Pneumonia, Mycoplasma - immunology; Pneumonia, Mycoplasma - pathology; Respiratory Mechanics; Respiratory Mechanics - physiology; Respiratory Tract Infections; Respiratory Tract Infections - drug therapy; Respiratory Tract Infections - immunology; Respiratory Tract Infections - pathology; Rodentia; Mycoplasma pneumoniae; Mycoplasmataceae; Mollicutes; Cethromycin; Infection; Respiratory tract; Mycoplasmatales; Vertebrata; Mammalia; Treatment; Mouse; Animal; Bacteriosis; Bacteria; Models; Antibacterial agent; Mycoplasmal infection
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.48.8.2897-2904.2004

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