Macrolides and β-Lactam Antibiotics Enhance C3b Deposition on the Surface of Multidrug-Resistant Streptococcus pneumoniae Strains by a LytA Autolysin-Dependent Mechanism

• Published in: Antimicrobial Agents and Chemotherapy Vol. 56; no. 11; pp. 5534 - 5540
• Main Authors: RAMOS-SEVILLANO, Elisa, RODRIGUEZ-SOSA, Cinthya, DIEZ-MARTINEZ, Roberto, GIMENEZ, María-José, OLMEDILLAS, Eduardo, GARCIA, Pedro, GARCIA, Ernesto, AGUILAR, Lorenzo, YUSTE, Jose
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.11.2012
• Subjects: Animals; Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial diseases; Bacterial Proteins; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; beta-Lactams; beta-Lactams - pharmacology; Biological and medical sciences; Cell Wall - drug effects; Cell Wall - enzymology; Complement C3b; Complement C3b - immunology; Complement C3b - pharmacology; Culture Media; Drug Resistance, Multiple, Bacterial - drug effects; Drug Resistance, Multiple, Bacterial - genetics; Human bacterial diseases; Immune Sera - chemistry; Immune Sera - immunology; Infectious diseases; Macrolides; Macrolides - pharmacology; Mechanisms of Action: Physiological Effects; Medical sciences; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mutation; N-Acetylmuramoyl-L-alanine Amidase; N-Acetylmuramoyl-L-alanine Amidase - genetics; N-Acetylmuramoyl-L-alanine Amidase - metabolism; Pharmacology. Drug treatments; Staphylococcal infections, streptococcal infections, pneumococcal infections; Streptococcus pneumoniae; Streptococcus pneumoniae - drug effects; Streptococcus pneumoniae - enzymology; Streptococcus pneumoniae - genetics; Enzyme; β-Lactams; Metalloendopeptidases; Autolysin; Macrolide; Strain; Streptococcus pneumoniae; Surface; Infection; Peptidases; Streptococcaceae; Antibiotic; Streptococcal infection; Multiple resistance; Bacteriosis; Bacteria; Hydrolases; Micrococcales; Protein synthesis inhibitor; Antibacterial agent; Mechanism of action; Complement C3b; Pneumococcal infection; Deposition
• ISSN: 0066-4804; 1098-6596; 1098-6596
• DOI: 10.1128/AAC.01470-12

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC