Luminol-Based Turn-On Fluorescent Sensor for Selective and Sensitive Detection of Sulfur Mustard at Ambient Temperature

• Published in: Analytical chemistry (Washington) Vol. 93; no. 2; pp. 1193 - 1199
• Main Authors: Singh, Virendra V, Kumar, Vinod, Biswas, Utpal, Boopathi, Mannan, Ganesan, Kumaran, Gupta, Arvind K
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 19.01.2021
• Subjects: Ambient temperature; Analytical chemistry; Chemistry; color; Fluorescence; Fluorescent Dyes - chemistry; Ionic liquids; Ions; Luminol - chemistry; Molecular Structure; Mustard gas; Mustard Gas - analysis; Room temperature; Selectivity; Spectrometry, Fluorescence; Sulfur; Temperature
• ISSN: 0003-2700; 1520-6882; 1520-6882
• DOI: 10.1021/acs.analchem.0c04464

We have explored a novel turn-on fluorescence detection of sulfur mustard (SM) at “room temperature”. The innovative protocol that uses the combination of luminol and an ionic liquid in water exhibits fluorescence detection of SM within seconds. In this simple, fast, and low-cost chemosensing method, luminol acts as the receptor as well as a signaling element, and the ionic liquid (1-ethyl-3-methylimidazolium dicyanamide) provides the requisite and polarizing medium to realize the detection at “room temperature”. Interestingly, with a higher concentration of a probe (0.56 mM), SM sensing can be visualized with the naked eye, leading to the formation of a fluorescent green color within a minute, thus expanding the application of the developed sensing technique for chromo-fluorogenic detection of SM. Excellent selectivity, sensitivity (LOD: 6 ppm), and chemosensing at ambient temperature make this methodology completely field-deployable.