Short- and long-term stability of SARS-CoV-2 antibodies on dried blood spots under different storage conditions

Dried blood spots (DBS) are currently widely used as a microsampling technique for different qualitative and quantitative serological assessments. Yet, there is a lack of long-term stability and storage condition studies. In our study, first, we assessed the stability of SARS-CoV-2 antibodies on DBS...

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Bibliographic Details
Published inMicrobiology spectrum Vol. 12; no. 12; p. e0111324
Main Authors Meyers, Eline, Coen, Anja, Padalko, Elizaveta, Cools, Piet
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 17.10.2024
Subjects
dried blood spots
freeze-thaw
Immunology
preservation
Research Article
SARS-CoV-2 antibodies
storage
preservation
storage
SARS-CoV-2 antibodies
freeze-thaw
dried blood spots
Online AccessGet full text
ISSN2165-0497
2165-0497
DOI10.1128/spectrum.01113-24

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Summary:Dried blood spots (DBS) are currently widely used as a microsampling technique for different qualitative and quantitative serological assessments. Yet, there is a lack of long-term stability and storage condition studies. In our study, first, we assessed the stability of SARS-CoV-2 antibodies on DBS up to 2 years post-collection. We believe that our data are not only important for future COVID-19 research but also for studies on other infections/diseases using DBS-based serology.
Bibliography:ObjectType-Article-1
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The authors declare no conflict of interest.
ISSN:2165-0497
2165-0497
DOI:10.1128/spectrum.01113-24