Managing Psychotropic Medications in Complex, Real-World Patients Using Comprehensive Therapeutic Drug Monitoring

There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are no readily available biomarkers to gauge treatment...

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Published inACS chemical neuroscience Vol. 8; no. 8; pp. 1641 - 1644
Main Authors Sutherland, Jeffrey J, Morrison, Ryan D, Daniels, J. Scott, Milne, Stephen B, Ryan, Timothy P
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 16.08.2017
Subjects
Drug Monitoring - methods
Humans
Mental Disorders - drug therapy
Precision Medicine
Psychotropic Drugs - therapeutic use
Adherence
medication therapy management
compliance
DDI
precision medicine
medical record reconciliation
pharmacogenetics
therapeutic drug monitoring
drug Interactions
Online AccessGet full text
ISSN1948-7193
1948-7193
DOI10.1021/acschemneuro.7b00209

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Abstract There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are no readily available biomarkers to gauge treatment success with psychotropic medications, often resulting in subjective determination of medication therapy effectiveness. The physiochemical properties of psychiatric medications in general lend themselves to quantitative measurement in blood, offering an avenue to optimize treatment for each patient. Herein, we describe a novel application that employs comprehensive therapeutic drug monitoring of both psychiatric and nonpsychiatric medications to holistically personalize therapy for complex psychiatry patients.
AbstractList There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are no readily available biomarkers to gauge treatment success with psychotropic medications, often resulting in subjective determination of medication therapy effectiveness. The physiochemical properties of psychiatric medications in general lend themselves to quantitative measurement in blood, offering an avenue to optimize treatment for each patient. Herein, we describe a novel application that employs comprehensive therapeutic drug monitoring of both psychiatric and nonpsychiatric medications to holistically personalize therapy for complex psychiatry patients.
There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are no readily available biomarkers to gauge treatment success with psychotropic medications, often resulting in subjective determination of medication therapy effectiveness. The physiochemical properties of psychiatric medications in general lend themselves to quantitative measurement in blood, offering an avenue to optimize treatment for each patient. Herein, we describe a novel application that employs comprehensive therapeutic drug monitoring of both psychiatric and nonpsychiatric medications to holistically personalize therapy for complex psychiatry patients.There are multiple treatment options for depression, anxiety, psychosis, and other psychiatric disorders, and psychiatry patients are often comorbid with complex, polypharmacy treatment regimens. Unlike cardiovascular disease and diabetes, there are no readily available biomarkers to gauge treatment success with psychotropic medications, often resulting in subjective determination of medication therapy effectiveness. The physiochemical properties of psychiatric medications in general lend themselves to quantitative measurement in blood, offering an avenue to optimize treatment for each patient. Herein, we describe a novel application that employs comprehensive therapeutic drug monitoring of both psychiatric and nonpsychiatric medications to holistically personalize therapy for complex psychiatry patients.
Author Morrison, Ryan D
Milne, Stephen B
Daniels, J. Scott
Sutherland, Jeffrey J
Ryan, Timothy P
AuthorAffiliation Sano Laboratories
Sano Informed Prescribing
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Cites_doi 10.1055/s-0031-1286287
10.1007/s00228-013-1504-x
10.1586/14779072.2016.1143359
10.1097/00007691-200404000-00012
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Keywords Adherence
medication therapy management
compliance
DDI
precision medicine
medical record reconciliation
pharmacogenetics
therapeutic drug monitoring
drug Interactions
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SubjectTerms Drug Monitoring - methods
Humans
Mental Disorders - drug therapy
Precision Medicine
Psychotropic Drugs - therapeutic use
Title Managing Psychotropic Medications in Complex, Real-World Patients Using Comprehensive Therapeutic Drug Monitoring
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