Xenopus From Basic Biology to Disease Models in the Genomic Era

• Main Author: Fainsod, Abraham
• Format: eBook
• Language: English
• Published: CRC Press 2022; Deptartment of Anatomy and Cell Biology George Washington University; Taylor & Francis
• Edition: 1
• Subjects: Biology, life sciences; BIOSCIENCEnetBASE; Cell Biology; Developmental Biology; Ecological science; Ecological science, the Biosphere; Evolution; Genetics; Genetics & Genomics; Genetics (non-medical); Life Sciences; Life sciences: general issues; LIFESCIENCEnetBASE; Mathematics and Science; Natural History; Nonfiction; SCI-TECHnetBASE; Science; STMnetBASE; the Biosphere; Xenopus; BMP4 Signaling; Notch Signaling; Gene Regulatory Networks; Neural Crest; Xenopus Embryos; Egg Extracts; Morphogenesis; HIRA; Amphibian Genomics; DNA Methylation; frog genome; BMP Signaling; Multiciliated Cells; WNT Signaling; Dorsal Mesoderm; Nuclear Transfer Embryos; NCCs; Xenopus Egg Extracts; Retinoic Acid Signaling; FGF Signaling; Cranial Neural Crest Cells; Vertebrate Development; DNA Replication; Xenopus Oocytes; Germ Layer; model organism; Xenopus Species; Neural Plate; Paraxial Mesoderm
• ISBN: 9780367505271; 0367505274; 0367505347; 9780367505349; 1000529770; 9781003050230; 9781000529777; 1003050239; 1000529819; 9781000529814
• DOI: 10.1201/9781003050230

This book focuses on the amphibian, Xenopus, one of the most commonly used model animals in the biological sciences. Over the past 50 years, the use of Xenopus has made possible many fundamental contributions to our knowledge in cell biology, developmental biology, molecular biology, and neurobiology. In recent years, with the completion of the genome sequence of the main two species and the application of genome editing techniques, Xenopus has emerged as a powerful system to study fundamental disease mechanisms and test treatment possibilities. Xenopus has proven an essential vertebrate model system for understanding fundamental cell and developmental biological mechanisms, for applying fundamental knowledge to pathological processes, for deciphering the function of human disease genes, and for understanding genome evolution. Key Features Provides historical context of the contributions of the model system Includes contributions from an international team of leading scholars Presents topics spanning cell biology, developmental biology, genomics, and disease model Describes recent experimental advances Incorporates richly illustrated diagrams and color images Related Titles Green, S. L. The Laboratory Xenopus sp. (ISBN 978-1-4200-9109-0) Faber, J. & P. D. Nieuwkoop. Normal Table of Xenopus laevis (Daudin): A Systematical & Chronological Survey of the Development from the Fertilized Egg till the End of Metamorphosis (ISBN 978-0-8153-1896-5) Jarret, R. L. & K. McCluskey. The Biological Resources of Model Organisms (ISBN 978-1-0320-9095-5)