Sigma proteins : evolution of the concept of sigma receptors

• Other Authors: Kim, Felix J. (Editor), Pasternak, Gavril W. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham, Switzerland : Springer, [2017]
• Series: Handbook of experimental pharmacology ; v. 244.
• Subjects: Sigma receptors.; elektronické knihy; electronic books
• ISBN: 9783319658537; 9783319658513
• ISSN: 1865-0325 ;
• Physical Description: 1 online resource (viii, 330 pages) : illustrations (chiefly color)

"Two sigma receptor subtypes have been proposed, sigma1 and 2. Much of our understanding of this system is based on biochemical and pharmacological characterization of the cloned sigma1 receptor subtype (Sigma1). It has become clear that sigma receptors are not canonical receptors. Sigma1 is hi...