Foodborne pathogens : virulence factors and host susceptibility

• Other Authors: Gurtler, Joshua B. (Editor), Doyle, Michael P., 1949- (Editor), Kornacki, Jeffrey L. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer, 2017.
• Series: Food microbiology and food safety series.
• Subjects: Foodborne diseases > Microbiology.; Pathogenic bacteria.; elektronické knihy; electronic books
• ISBN: 9783319568362; 9783319568348
• Physical Description: 1 online resource

Foodborne illnesses continue to be a major public health concern. All members of a particular bacterial genera (e.g., Salmonella, Campylobacter) or species (e.g., Listeria monocytogenes, Cronobacter sakazakii) are often treated by public health and regulatory agencies as being equally pathogenic; ho...

Table of Contents:

• Virulence Book Introduction; Part I: Foodborne Pathogens and Virulence Factors; Advantages of Virulotyping Pathogens Over Traditional Identification and Characterization Methods; Introduction; Virulotyping Enterohemorrhagic E. coli; Virulotyping Salmonella Serovars; More Clinical Benefits to Virulotyping; Conclusion; References; Varying Pathogenicity of Campylobacter jejuni Isolates; Introduction; Epidemiology and Transmission Routes of C. jejuni; Strain Variability; Molecular Virulence Mechanisms of C. jejuni; Adhesion to Epithelial Cells; Cellular Invasion.
• Transmigration Across the Epithelial Barrier Intracellular Survival; Interaction with Immune Cells; Animal Infection Models; Conclusions and Perspectives; References; Strain-Specific Virulence Differences in Listeria monocytogenes: Current Perspectives in Addressing an Old and Vexing Issue; Omics Tools in the Determination and Characterization of Differences in Virulence Among Different Strains of Listeria monocytogenes; Virulence-Related Genomic Sequences with Non-homogenous Distribution in L. monocytogenes.
• Whole Genome Sequencing (WGS)-Based Insights on Virulence Differences Among L. monocytogenes Strains Strain-Specific Differences in Virulence:Insights from Epidemiological Investigations; Recent Applications of Genotype Surveillance, Whole Genome Sequencing and Targeted Assessments to Identify L. monocytogenes Populations (Clones) Varying in Virulence Potential and Host System Tropism; Challenges and Opportunities Regarding Determination of Hyper- and Hypovirulent Clones.
• Experimental Evidence for Hypervirulent and Hypovirulent Clones with Different Invasiveness Potential, and Some Caveats on the Choice of Prototype Strains Are There Virulence Determinants Unique to Hypervirulent Clones?; Conclusions; References; The Listeria monocytogenes Triad for Success: Food Matrix, Stress Response and Virulence; Introduction; Food Production and Induction of Stress Responses; Tolerance Responses that Influence L. monocytogenes Survival; Heat Tolerance Response; Cold Tolerance Response; Osmotolerance Response; Tolerance Response to Low pH.
• Systems that Sustain L. monocytogenes Acid ResistanceF1F0 ATPase Complex; The Glutamate Decarboxylase Acid Resistance (GAD) System; Arginine Deiminase (ADI) System and Thiamine; Sensors and Regulators; Oxidative Stress; Bile Stress; Cross-Adaptation; The Relationship Between the Food Matrix, Stress Response and Virulence of L. monocytogenes; Conclusions; References; Virulence Traits in the Cronobacter Genus; General Overview; Background to Cronobacter spp.; Clinical Aspects of Cronobacter Infection; Infection of the Gastrointestinal Tract: Necrotizing Enterocolitis (NEC).