Asymmetric cell division in development, differentiation and cancer

This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline...

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Bibliographic Details
Other Authors: Tassan, Jean-Pierre, (Editor), Kubiak, Jacek Z., (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2017.
Series: Results and problems in cell differentiation ; 61.
Subjects:
Cell division.
elektronické knihy
electronic books
ISBN: 9783319531502
9783319531496
Physical Description: 1 online resource (vi, 421 pages) : illustrations (some color)

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245 0 0 |a Asymmetric cell division in development, differentiation and cancer /  |c Jean-Pierre Tassan, Jacek Z. Kubiak, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource (vi, 421 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Results and problems in cell differentiation,  |x 0080-1844 ;  |v volume 61 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields. 
504 |a Includes bibliographical references. 
505 0 |a 1 Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach -- 2 Spatiotemporal models of asymmetric cell division cycle in Caulobacter crescentus -- 3 Intrinsic and extrinsic determinants linking spindle pole fate, spindle polarity and asymmetric cell division in the budding yeast S. cerevisiae -- 4 Wnt signaling polarizes C. elegans asymmetric cell divisions during development -- 5 Asymmetric cell division in the one-cell C.elegans embryo: multiple steps to generate cell size asymmetry -- 6 Size matters: how C. elegans asymmetric divisions regulate apoptosis -- 7 The midbody and its remnant in cell polarization and asymmetric cell division -- 8 Drosophila melanogaster neuroblasts: a model for asymmetric stem cell divisions -- 9 Asymmetric divisions in oogenesis -- 10 Asymmetric localization and distribution of factors determining cell fate during early development of Xenopus laevis -- 11 Asymmetries in cell division, cell size and furrowing in the Xenopus laevis embryo -- 12 Asymmetric and unequal cell divisions in ascidian embryos -- 13 Asymmetries and symmetries in the mouse oocyte and zygote -- 14 Symmetry does not come for free -- cellular mechanisms to achieve a symmetric cell division -- 15 A Comparative Perspective on Wnt/?-catenin Signalling in Cell Fate Determination -- 16 Extracellular regulation of the mitotic spindle and fate determinants driving asymmetric cell division -- 17 Regulation of asymmetric cell division in mammalian neural stem and cancer precursor cells -- 18 Molecular programs underlying asymmetric stem cell division and their disruption in malignancy. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Cell division. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Tassan, Jean-Pierre,  |e editor. 
700 1 |a Kubiak, Jacek Z.,  |e editor. 
776 0 8 |i Print version:  |t Asymmetric cell division in development, differentiation and cancer.  |d Cham, Switzerland : Springer, 2017  |z 3319531492  |z 9783319531496  |w (OCoLC)967584761 
830 0 |a Results and problems in cell differentiation ;  |v 61. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-53150-2  |y Plný text 
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999 |c 97273  |d 97273 
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