Alternatives for Dermal Toxicity Testing

This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin cor...

Full description

Saved in:
Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Eskes, Chantra. (Editor), van Vliet, Erwin. (Editor), Maibach, Howard I. (Editor)
Format: eBook
Language: English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Subjects:
Medicine.
Pharmacology.
Dermatology.
Animal models in research.
elektronické knihy
electronic books
ISBN: 9783319503530
Physical Description: XX, 592 p. 92 illus., 61 illus. in color. online resource.

Cover

Table of contents

LEADER 03229nam a22004095i 4500
001 100959
003 CZ-ZlUTB
005 20240914113119.0
006 m o d
007 cr nn 008mamaa
008 171122s2017 gw | s |||| 0|eng d
020 |a 9783319503530 
024 7 |a 10.1007/978-3-319-50353-0  |2 doi 
245 1 0 |a Alternatives for Dermal Toxicity Testing /  |c edited by Chantra Eskes, Erwin van Vliet, Howard I. Maibach. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2017. 
300 |a XX, 592 p. 92 illus., 61 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
505 0 |a Introduction -- Concepts -- Skin irritation -- Skin corrosion -- Skin sensitization -- UV-induced effects (phototoxicity & photoallergy) -- Skin genotoxicity -- Other exploratory areas of relevance. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol, possible adaptations, and challenges and opportunities. The closing section addresses exploratory areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, the use of alternative methods for infections and inflammatory diseases, novel complex skin models, and high-throughput screening techniques. Dermal toxicity is an area in which alternatives to the use of animal testing have already gained scientific, industrial, and regulatory acceptance. Practitioners and researchers alike will find Alternatives for Dermal Toxicity Testing to be an ideal source of reliable, up-to-date information on all aspects of the available test methods and likely future directions. 
650 0 |a Medicine. 
650 0 |a Pharmacology. 
650 0 |a Dermatology. 
650 0 |a Animal models in research. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Eskes, Chantra.  |e editor. 
700 1 |a van Vliet, Erwin.  |e editor. 
700 1 |a Maibach, Howard I.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9783319503516 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-50353-0  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 100959  |d 100959 
993 |x NEPOSILAT  |y EIZ 

Similar Items