Study on the teratogenesis and embryo toxicity of mixture of organophosphorus pesticide in rats / 有机磷农药混剂对大鼠的胚胎毒性和致畸性研究

目的观察敌敌畏、乐果和马拉硫磷对大鼠的致畸作用.方法将SD孕鼠随机分为4组,即有机磷农药混剂20.4、30.6、40.8 mg/kg 3个剂量染毒组和阴性对照组.分别经口给予不同剂量的有机磷农药混剂和生理盐水,进行传统的致畸实验,观察母鼠及胎仔的情况.结果有机磷农药混剂对母鼠体质量有影响,40.8 mg/kg组体质量明显减轻.孕鼠的生殖能力包括平均黄体数、胎盘重和窝重与阴性对照组比较也有显著性差异(P＜0.05).染毒组胎仔体质量与阴性对照组比较有显著性差异(P＜0.05).40.8 mg/kg和30.6 mg/kg组还出现死胎、吸收胎和畸胎,但与阴性对照组比较无显著性差异(P＞0.05).结...

Full description

Saved in:
Bibliographic Details
Published inXi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban no. 6; p. 562
Main Authors 孙晓英, 于燕, 张振军, 边学峰, 陈庆
Format Journal Article
LanguageChinese
Published Xi'an Xi'an Jiaotong University 01.01.2005
Online AccessGet full text
ISSN1671-8259

Cover

Abstract 目的观察敌敌畏、乐果和马拉硫磷对大鼠的致畸作用.方法将SD孕鼠随机分为4组,即有机磷农药混剂20.4、30.6、40.8 mg/kg 3个剂量染毒组和阴性对照组.分别经口给予不同剂量的有机磷农药混剂和生理盐水,进行传统的致畸实验,观察母鼠及胎仔的情况.结果有机磷农药混剂对母鼠体质量有影响,40.8 mg/kg组体质量明显减轻.孕鼠的生殖能力包括平均黄体数、胎盘重和窝重与阴性对照组比较也有显著性差异(P＜0.05).染毒组胎仔体质量与阴性对照组比较有显著性差异(P＜0.05).40.8 mg/kg和30.6 mg/kg组还出现死胎、吸收胎和畸胎,但与阴性对照组比较无显著性差异(P＞0.05).结论在实验剂量范围内,有机磷农药混剂对大鼠有母体和胚胎毒性.
AbstractList 目的观察敌敌畏、乐果和马拉硫磷对大鼠的致畸作用.方法将SD孕鼠随机分为4组,即有机磷农药混剂20.4、30.6、40.8 mg/kg 3个剂量染毒组和阴性对照组.分别经口给予不同剂量的有机磷农药混剂和生理盐水,进行传统的致畸实验,观察母鼠及胎仔的情况.结果有机磷农药混剂对母鼠体质量有影响,40.8 mg/kg组体质量明显减轻.孕鼠的生殖能力包括平均黄体数、胎盘重和窝重与阴性对照组比较也有显著性差异(P＜0.05).染毒组胎仔体质量与阴性对照组比较有显著性差异(P＜0.05).40.8 mg/kg和30.6 mg/kg组还出现死胎、吸收胎和畸胎,但与阴性对照组比较无显著性差异(P＞0.05).结论在实验剂量范围内,有机磷农药混剂对大鼠有母体和胚胎毒性.
Author 孙晓英
边学峰
陈庆
张振军
于燕
Author_xml – sequence: 1
  fullname: 孙晓英
– sequence: 2
  fullname: 于燕
– sequence: 3
  fullname: 张振军
– sequence: 4
  fullname: 边学峰
– sequence: 5
  fullname: 陈庆
BookMark eNrjYmDJy89LZWHgNDQzN9S1MDK15GDgLS7OTDIwMDQwNTQyMeVkWBhcUppSqZCfp1CSkapQklqUWJKfnpqXWpxZrJCYl6KQmptUVJmvUJJfkZmcWQJUmKaQm1lRUlqUCmLmF6Un5uUXZOQXA3FRabFCQWpxCVBhSqpCZp4C0KxiBX2FZ3M6n83Z9Xzx9qdtc170rn-2ffvTzqan63c-XbL85Z4Fz2e1vGie9aK579n6Sc8alj-d1POifcvzqTuA7OcLpjxfuY2HgTUtMac4lRdKczMou7mGOHvoFhTlF5YC7YvPyi8tygNKxRsZWhiZGJqaGlgaE6cKAHipdQA
ContentType Journal Article
Copyright Copyright Xi'an Jiaotong University 2005
Copyright_xml – notice: Copyright Xi'an Jiaotong University 2005
DBID 3V.
7X7
7XB
8FI
8FJ
8FK
ABUWG
AFKRA
BENPR
BVBZV
CCPQU
FYUFA
GHDGH
K9.
M0S
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
DatabaseName ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central
East & South Asia Database
ProQuest One
Proquest Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
ProQuest Health & Medical Collection
Proquest Central Premium
ProQuest One Academic
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
DatabaseTitle ProQuest One Academic Middle East (New)
ProQuest One Academic Eastern Edition
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest One Health & Nursing
ProQuest Central China
ProQuest Hospital Collection (Alumni)
East & South Asia Database
ProQuest Central
ProQuest Health & Medical Complete
ProQuest Health & Medical Research Collection
Health Research Premium Collection
ProQuest One Academic UKI Edition
Health and Medicine Complete (Alumni Edition)
ProQuest One Academic
ProQuest Central (New)
ProQuest Central (Alumni)
ProQuest One Academic (New)
DatabaseTitleList ProQuest One Academic Middle East (New)
Database_xml – sequence: 1
  dbid: 7X7
  name: Health & Medical Collection
  url: https://search.proquest.com/healthcomplete
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
GroupedDBID ---
-05
3V.
7X7
7XB
8FI
8FJ
8FK
ABUWG
AFKRA
ALMA_UNASSIGNED_HOLDINGS
BENPR
BPHCQ
BVBZV
BVXVI
CCEZO
CCPQU
CIEJG
FYUFA
HMCUK
K9.
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
PROAC
UKHRP
ID FETCH-proquest_journals_21824155093
IEDL.DBID BENPR
ISSN 1671-8259
IngestDate Tue Oct 07 07:00:59 EDT 2025
IsPeerReviewed false
IsScholarly true
Issue 6
Language Chinese
LinkModel DirectLink
MergedId FETCHMERGED-proquest_journals_21824155093
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
PQID 2182415509
PQPubID 3912278
ParticipantIDs proquest_journals_2182415509
PublicationCentury 2000
PublicationDate 20050101
PublicationDateYYYYMMDD 2005-01-01
PublicationDate_xml – month: 01
  year: 2005
  text: 20050101
  day: 01
PublicationDecade 2000
PublicationPlace Xi'an
PublicationPlace_xml – name: Xi'an
PublicationTitle Xi'an jiao tong da xue xue bao. Journal of Xi'an Jiaotong University (medical sciences). Yi xue ban
PublicationYear 2005
Publisher Xi'an Jiaotong University
Publisher_xml – name: Xi'an Jiaotong University
SSID ssib001051245
ssib051375640
ssib012416230
ssib012869364
ssib038076391
ssib022315977
ssib001104403
ssib052002713
ssib002263349
ssib036440245
ssib002039773
ssib006705401
ssj0001537995
Score 3.322028
Snippet 目的观察敌敌畏、乐果和马拉硫磷对大鼠的致畸作用.方法将SD孕鼠随机分为4组,即有机磷农药混剂20.4、30.6、40.8 mg/kg 3个剂量染毒组和阴性对照组.分别经口给予不同剂量的有机...
SourceID proquest
SourceType Aggregation Database
StartPage 562
Title Study on the teratogenesis and embryo toxicity of mixture of organophosphorus pesticide in rats / 有机磷农药混剂对大鼠的胚胎毒性和致畸性研究
URI https://www.proquest.com/docview/2182415509
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVPQU
  databaseName: East & South Asia Database
  issn: 1671-8259
  databaseCode: BVBZV
  dateStart: 20020101
  customDbUrl:
  isFulltext: true
  dateEnd: 20210131
  titleUrlDefault: https://search.proquest.com/eastsouthasia
  omitProxy: false
  ssIdentifier: ssj0001537995
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: Health & Medical Collection
  issn: 1671-8259
  databaseCode: 7X7
  dateStart: 20020101
  customDbUrl:
  isFulltext: true
  dateEnd: 20210131
  titleUrlDefault: https://search.proquest.com/healthcomplete
  omitProxy: true
  ssIdentifier: ssj0001537995
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central
  issn: 1671-8259
  databaseCode: BENPR
  dateStart: 20020101
  customDbUrl: http://www.proquest.com/pqcentral?accountid=15518
  isFulltext: true
  dateEnd: 20210131
  titleUrlDefault: https://www.proquest.com/central
  omitProxy: true
  ssIdentifier: ssj0001537995
  providerName: ProQuest
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQAdbQSWmJxua6KYlpRrqgA7p0LU3MjXQTLS2M0lKBScg4BbR32NfPzCPUxCvCNIKJwQ-2Fwa0rBJWJoIL6pT8ZNAYuT7opHFQ5WdgaV9QqAu6NQo0uwq7QiMRerVCii34iDFmBlYj0MlYLAysTq5-AUFIHSBgBYc0jwas_EyQD6QzMgA1iJArODNjY6QOipk5qIkDzxFAswyB7QcDBN_CzNIY0QEB1r2GyAe8AaVMDJDsB532DmwiwM0zNTQ2NzVDnL4COhPJyBxa4UL2PRuDTnAD9SLNzA11gd07S4xKBFwzugky8EObtAqOkDQoxMBUlSHCsBC0QLFSIT9PAdjCVAAf3ZyfDipXM4sVEvNSFFJzk4oq8xVK8isyk4EdAYX8NIXczArQdAaICb5rKr8gI78YiItKixUKQIeBJGempCpk5ikAzSpW0Fd4Nqfz2Zxdzxdvf9o250Xv-mfbtz_tbHq6fufTJctf7lnwfFbLi-ZZL5r7nq2f9Kxh-dNJPS_atzyfugPIfr5gyvOV20QZlN1cQ5w9dGH-iofmq-J4RCowFmNgycvPS5VgUEg0N0mzTAR2nBLNzUwsjJItUw1MTZOSUwzNk1OA3f9ESQYZfCZJ4ZeWZuACH9cKHnaRYWApKSpNlQU2REqS5BiYzSPM5aBpDADgp-oX
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQAdbQSWmJxua6KYlpRrqgA7p0LU3MjXQTLS2M0lKBScg4BbR32NfPzCPUxCvCNIKJoQe2Fwa0rBJWJoIL6pT8ZNAYuT7opHFQ5WdgaV9QqAu6NQo0uwq7QiMRerVCii34iDHoxg7v1MpyYBeu2NbTBRjfqkZGbq4hzh66MPPjodFVHI8w3BioipmB1cTYxBLYlWN1cvULCELqPgGrR6RZOGDVaYJ8nJ2RAag5hVw9mhkbI3VvzMxBDSR4fgKaZQhsfRgg-BZmlsaI7guw5jZEPh4OKGVigGQ_6Kx4YAMDbp6pobG5qRni7BbQiUpG5tDqGrJr2hh0_huoD2pmbqgL7BxaYlRB4HrVTZCBH9ogVnCEpGAhBqaqDBGGhaDljZUK-XkKwPapAvjg5_x0UKmcWayQmJeikJqbVFSZr1CSX5GZDOxGKOSnKeRmVoAmQ0BM8E1V-QUZ-cVAXFRarFAAOkokOTMlVSEzTwFoVrGCvsKzOZ3P5ux6vnj707Y5L3rXP9u-_Wln09P1O58uWf5yz4Lns1peNM960dz3bP2kZw3Ln07qedG-5fnUHUD28wVTnq_cJsqgTEQ0izGw5OXnpUowKCSam6RZJgK7XYnmZiYWRsmWqQampknJKYbmySkGJmaJkgwy-EySwi8tz8DpEeLrE-_j6ectzcAFPvgVPIAjw8BSUlSaKgts0pQkyUFTmgKDHmlJFQBoZg5n
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Study+on+the+teratogenesis+and+embryo+toxicity+of+mixture+of+organophosphorus+pesticide+in+rats+%2F+%E6%9C%89%E6%9C%BA%E7%A3%B7%E5%86%9C%E8%8D%AF%E6%B7%B7%E5%89%82%E5%AF%B9%E5%A4%A7%E9%BC%A0%E7%9A%84%E8%83%9A%E8%83%8E%E6%AF%92%E6%80%A7%E5%92%8C%E8%87%B4%E7%95%B8%E6%80%A7%E7%A0%94%E7%A9%B6&rft.jtitle=Xi%27an+jiao+tong+da+xue+xue+bao.+Journal+of+Xi%27an+Jiaotong+University+%28medical+sciences%29.+Yi+xue+ban&rft.au=%E5%AD%99%E6%99%93%E8%8B%B1&rft.au=%E4%BA%8E%E7%87%95&rft.au=%E5%BC%A0%E6%8C%AF%E5%86%9B&rft.au=%E8%BE%B9%E5%AD%A6%E5%B3%B0&rft.date=2005-01-01&rft.pub=Xi%27an+Jiaotong+University&rft.issn=1671-8259&rft.issue=6&rft.spage=562
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1671-8259&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1671-8259&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1671-8259&client=summon