RECURRENCE RISK PROGNOSIS MODEL OF HER2-POSITIVE T1N0 BREAST INVASIVE DUCTAL CARCINOMA PATIENT

• Main Authors: YUAN, Peng, GAO, Songlin
• Format: Patent
• Language: Chinese; English; French
• Published: 30.11.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

A method and device for predicting whether a subject, i.e., an HER2-positive T1N0 breast invasive ductal carcinoma patient, has a poor prognosis. The method comprises calculating the total score of the subject, which is equal to the sum of the age score, the staging score, the ER/PR state score, and the Ki-67 expression score; if the total score is less than a truncation value, indicating that the subject has a poor prognosis; and if the total score is greater than the truncation value, indicating that the prognosis is good, wherein the truncation value ranges from 40.0 to 50.0, preferably 42.7. Procédé et dispositif permettant de prédire si un sujet, c'est-à-dire une patiente atteinte d'un carcinome canalaire invasif du sein T1N0 positif à HER2, présente un pronostic défavorable. Le procédé consiste à calculer le score total du sujet, qui est égal à la somme du score d'âge, du score de stadification, du score d'état ER/PR et du score d'expression de Ki-67; si le score total est inférieur à une valeur de tron