Mixed mode cation exchange chromatography ligands based on 1,3-dioxoisoindolin-2-yl structures
The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-dioxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix be...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
22.08.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-dioxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of one, two, three, four, or five atoms between the hydrophobic group and the support matrix. |
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| AbstractList | The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-dioxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of one, two, three, four, or five atoms between the hydrophobic group and the support matrix. |
| Author | Liao, Jiali Belisle, Christopher Lozano, Edwin |
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| Notes | Application Number: US202217696917 |
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| Snippet | The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic... |
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| Title | Mixed mode cation exchange chromatography ligands based on 1,3-dioxoisoindolin-2-yl structures |
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