女性生殖道同期发生的黏液性上皮化生和肿瘤14例分析
R373.3; 目的 探讨女性生殖道同期发生的黏液性上皮化生和肿瘤(synchronous mucinous metaplasia and neoplasia of the female genital tract,SMMN-FGT)的临床表现、病理特征、诊治方法及预后.方法 回顾性分析2014年10月至2020年4月复旦大学附属妇产科医院诊断的14例SMMN-FGT患者的临床资料和随访记录.结果 发病中位年龄为46岁(33～70岁),初发症状主要为阴道排液(8/14)及卵巢囊肿(4/14).所有行HPV检查的患者(13/14)结果均为阴性.所有患者均接受手术治疗,其中7例行全子宫+双附件切除...
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| Published in | 复旦学报（医学版） Vol. 49; no. 3; pp. 402 - 410 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
复旦大学附属妇产科医院妇科 上海 200011%复旦大学附属妇产科医院病理科 上海 200011%复旦大学附属妇产科医院信息科 上海 200011
30.05.2022
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-8467 |
| DOI | 10.3969/j.issn.1672-8467.2022.03.013 |
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| Abstract | R373.3; 目的 探讨女性生殖道同期发生的黏液性上皮化生和肿瘤(synchronous mucinous metaplasia and neoplasia of the female genital tract,SMMN-FGT)的临床表现、病理特征、诊治方法及预后.方法 回顾性分析2014年10月至2020年4月复旦大学附属妇产科医院诊断的14例SMMN-FGT患者的临床资料和随访记录.结果 发病中位年龄为46岁(33～70岁),初发症状主要为阴道排液(8/14)及卵巢囊肿(4/14).所有行HPV检查的患者(13/14)结果均为阴性.所有患者均接受手术治疗,其中7例行全子宫+双附件切除术,4例行广泛全子宫+双附件切除术+盆腔淋巴结清扫术,3例行全子宫+双侧输卵管切除术,保留卵巢.术后病理提示14例病变累及子宫内膜,13例累及宫颈,9例累及输卵管,9例累及卵巢,7例同时累及宫颈、子宫内膜,输卵管及卵巢.8例患者进展为恶性肿瘤,术后接受辅助治疗.随访14～80个月,1例因复发死亡,13例继续随访中.结论 SMMN-FGT是一组同时累及女性生殖道多个部位的黏液性病变,阴道排液多为其首发症状,其宫颈病变与HPV感染无关.治疗以手术为主,合并恶性病变患者须行辅助治疗,预后有待进一步随访. |
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| AbstractList | R373.3; 目的 探讨女性生殖道同期发生的黏液性上皮化生和肿瘤(synchronous mucinous metaplasia and neoplasia of the female genital tract,SMMN-FGT)的临床表现、病理特征、诊治方法及预后.方法 回顾性分析2014年10月至2020年4月复旦大学附属妇产科医院诊断的14例SMMN-FGT患者的临床资料和随访记录.结果 发病中位年龄为46岁(33～70岁),初发症状主要为阴道排液(8/14)及卵巢囊肿(4/14).所有行HPV检查的患者(13/14)结果均为阴性.所有患者均接受手术治疗,其中7例行全子宫+双附件切除术,4例行广泛全子宫+双附件切除术+盆腔淋巴结清扫术,3例行全子宫+双侧输卵管切除术,保留卵巢.术后病理提示14例病变累及子宫内膜,13例累及宫颈,9例累及输卵管,9例累及卵巢,7例同时累及宫颈、子宫内膜,输卵管及卵巢.8例患者进展为恶性肿瘤,术后接受辅助治疗.随访14～80个月,1例因复发死亡,13例继续随访中.结论 SMMN-FGT是一组同时累及女性生殖道多个部位的黏液性病变,阴道排液多为其首发症状,其宫颈病变与HPV感染无关.治疗以手术为主,合并恶性病变患者须行辅助治疗,预后有待进一步随访. |
| Author | 董戌晖 陈默 李佳佳 尧良清 李勤 陶祥 朱辰琪 |
| AuthorAffiliation | 复旦大学附属妇产科医院妇科 上海 200011%复旦大学附属妇产科医院病理科 上海 200011%复旦大学附属妇产科医院信息科 上海 200011 |
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| Author_FL | YAO Liang-qing ZHU Chen-qi DONG Xu-hui LI Qin LI Jia-jia CHEN Mo TAO Xiang |
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| Keywords | 预后 黏液细胞分化 女性生殖道 胃型分化 临床特征 |
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| Title | 女性生殖道同期发生的黏液性上皮化生和肿瘤14例分析 |
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