基于CT定量探讨不同级别慢性阻塞性肺疾病患者肺气肿肺叶分布

R816%R563; 目的 探讨不同级别慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者肺气肿肺叶分布的特点.方法 收集COPD患者61例及正常对照90例,均行吸气相及呼气相CT扫描,COPD患者分为轻度组(COPD 1级与2级)和重度组(COPD 3级与4级).所得图像导入"数字肺"自动检测平台进行分析,肺气肿肺叶分布情况以各肺叶低密度区(low attenuation area,LAA)容积占全肺低密度区容积的百分比(percentage of LAA,LAA％)表示,低于-910 HU和-950 HU为肺气肿...

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Published in西安交通大学学报（医学版） Vol. 40; no. 2; pp. 182 - 186
Main Authors 师美娟, 沈聪, 于楠, 银楠, 王君, 黄晓旗, 郭佑民
Format Journal Article
LanguageChinese
Published 西安交通大学第二附属医院,陕西西安,710004%西安交通大学第一附属医院,陕西西安,710061%陕西中医药大学影像科,陕西咸阳,712000%延安大学附属医院影像科,陕西延安,716000 01.03.2019
Subjects
慢性阻塞性肺疾病
肺叶分布
计算机断层成像
肺气肿定量
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ISSN1671-8259
DOI10.7652/jdyxb201902003

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Abstract R816%R563; 目的 探讨不同级别慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者肺气肿肺叶分布的特点.方法 收集COPD患者61例及正常对照90例,均行吸气相及呼气相CT扫描,COPD患者分为轻度组(COPD 1级与2级)和重度组(COPD 3级与4级).所得图像导入"数字肺"自动检测平台进行分析,肺气肿肺叶分布情况以各肺叶低密度区(low attenuation area,LAA)容积占全肺低密度区容积的百分比(percentage of LAA,LAA％)表示,低于-910 HU和-950 HU为肺气肿.采用SPSS 22.0方差分析比较各组间LAA％的差异.结果 吸、呼气相中,轻度COPD组较正常组右肺上叶的LAA-910％及LAA-950％明显增加,右肺中叶的LAA-910％及LAA-950％显著减少,差异有统计学意义(P<0.05).与轻度COPD组比较,吸、呼气相中,重度COPD组均有双肺下叶LAA-910％及LAA-950％显著增加,左肺上叶LAA-910％及LAA-950％显著减少;呼气相中,另有右肺上叶LAA-910％及右肺中叶的LAA-910％及LAA-950％显著减小,差异有统计学意义(P<0.05).吸、呼气相中,重度COPD组较正常组右肺中叶及左肺上叶的LAA-910％及LAA-950％显著减小,左肺下叶的LAA-910％及LAA-950％显著增加;呼气相中,另有右肺上叶及下叶的LAA-910％及LAA-950％显著增加,差异有统计学意义(P<0.05).结论 轻度COPD患者的肺气肿在两上肺比例较大,重度COPD患者肺气肿在两下肺所占的比例明显增加.
AbstractList R816%R563; 目的 探讨不同级别慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者肺气肿肺叶分布的特点.方法 收集COPD患者61例及正常对照90例,均行吸气相及呼气相CT扫描,COPD患者分为轻度组(COPD 1级与2级)和重度组(COPD 3级与4级).所得图像导入"数字肺"自动检测平台进行分析,肺气肿肺叶分布情况以各肺叶低密度区(low attenuation area,LAA)容积占全肺低密度区容积的百分比(percentage of LAA,LAA％)表示,低于-910 HU和-950 HU为肺气肿.采用SPSS 22.0方差分析比较各组间LAA％的差异.结果 吸、呼气相中,轻度COPD组较正常组右肺上叶的LAA-910％及LAA-950％明显增加,右肺中叶的LAA-910％及LAA-950％显著减少,差异有统计学意义(P<0.05).与轻度COPD组比较,吸、呼气相中,重度COPD组均有双肺下叶LAA-910％及LAA-950％显著增加,左肺上叶LAA-910％及LAA-950％显著减少;呼气相中,另有右肺上叶LAA-910％及右肺中叶的LAA-910％及LAA-950％显著减小,差异有统计学意义(P<0.05).吸、呼气相中,重度COPD组较正常组右肺中叶及左肺上叶的LAA-910％及LAA-950％显著减小,左肺下叶的LAA-910％及LAA-950％显著增加;呼气相中,另有右肺上叶及下叶的LAA-910％及LAA-950％显著增加,差异有统计学意义(P<0.05).结论 轻度COPD患者的肺气肿在两上肺比例较大,重度COPD患者肺气肿在两下肺所占的比例明显增加.
Author 郭佑民
银楠
黄晓旗
师美娟
于楠
王君
沈聪
AuthorAffiliation 西安交通大学第二附属医院,陕西西安,710004%西安交通大学第一附属医院,陕西西安,710061%陕西中医药大学影像科,陕西咸阳,712000%延安大学附属医院影像科,陕西延安,716000
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SHI Mei-juan
SHEN Cong
GUO You-min
YU Nan
WANG Jun
YIN Nan
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Keywords 慢性阻塞性肺疾病
肺叶分布
计算机断层成像
肺气肿定量
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Title 基于CT定量探讨不同级别慢性阻塞性肺疾病患者肺气肿肺叶分布
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