基于下丘脑-垂体-性腺轴探析补肾法治疗2型糖尿病生精障碍的思路

R322.54%R587.1; 糖尿病(DM)高血糖病理状态是导致男性生精障碍的重要因素之一,下丘脑-垂体-性腺(HPG)轴是人体全身植物性功能、神经内分泌网络的重要枢纽,生理上主导人类生殖及生长发育,病理上又可受到DM高血糖病理状态的影响,是 2 型糖尿病(T2DM)生精障碍发生、发展过程中的关键机制之一,肾虚是生精障碍和T2DM共同的病因病机.肾藏精所体现的"主生殖、生髓充脑"功能与HPG轴功能相似,补肾法对HPG轴功能具有调节改善作用,为补肾法治疗T2DM生精障碍奠定理论基础.补肾经典方剂在治疗DM与生精障碍上相得益彰,为临床以补肾法防治T2DM生精障碍之不育症提供了...

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Published in中国全科医学 Vol. 27; no. 33; pp. 4210 - 4214
Main Authors 卢威, 杨云松, 林连美, 刘琼, 赵敏, 李佳, 梁凤霞, 吴松
Format Journal Article
LanguageChinese
Published 430061 湖北省武汉市,湖北中医药大学中医临床学院 20.11.2024
430061 湖北省武汉市,针灸治未病湖北省协同创新中心%430061 湖北省武汉市,湖北中医药大学中医临床学院%430065 湖北省武汉市,湖北中医药大学基础医学院%430061 湖北省武汉市,针灸治未病湖北省协同创新中心
430061 湖北省武汉市,湖北中医药大学针灸骨伤学院
Subjects
Dyszoospermia
Diabetes mellitus,type 2
生精障碍
Reinforcing kidney
糖尿病,2型
Theoretical discussion
补肾
理论探讨
Hypothalamo-hypophyseal system
下丘脑-垂体系统
Online AccessGet full text
ISSN1007-9572
DOI10.12114/j.issn.1007-9572.2023.0644

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Abstract R322.54%R587.1; 糖尿病(DM)高血糖病理状态是导致男性生精障碍的重要因素之一,下丘脑-垂体-性腺(HPG)轴是人体全身植物性功能、神经内分泌网络的重要枢纽,生理上主导人类生殖及生长发育,病理上又可受到DM高血糖病理状态的影响,是 2 型糖尿病(T2DM)生精障碍发生、发展过程中的关键机制之一,肾虚是生精障碍和T2DM共同的病因病机.肾藏精所体现的"主生殖、生髓充脑"功能与HPG轴功能相似,补肾法对HPG轴功能具有调节改善作用,为补肾法治疗T2DM生精障碍奠定理论基础.补肾经典方剂在治疗DM与生精障碍上相得益彰,为临床以补肾法防治T2DM生精障碍之不育症提供了思路和方法.
AbstractList R322.54%R587.1; 糖尿病(DM)高血糖病理状态是导致男性生精障碍的重要因素之一,下丘脑-垂体-性腺(HPG)轴是人体全身植物性功能、神经内分泌网络的重要枢纽,生理上主导人类生殖及生长发育,病理上又可受到DM高血糖病理状态的影响,是 2 型糖尿病(T2DM)生精障碍发生、发展过程中的关键机制之一,肾虚是生精障碍和T2DM共同的病因病机.肾藏精所体现的"主生殖、生髓充脑"功能与HPG轴功能相似,补肾法对HPG轴功能具有调节改善作用,为补肾法治疗T2DM生精障碍奠定理论基础.补肾经典方剂在治疗DM与生精障碍上相得益彰,为临床以补肾法防治T2DM生精障碍之不育症提供了思路和方法.
Abstract_FL Diabetic hyperglycemia in males is a significant contributing factor to the development of spermatogenesis disorder.The hypothalamic-pituitary-gonadal(HPG)axis serves as a crucial center for autonomic sexual function and the neuroendocrine network within the human body.It dominates physiological prominence in human reproduction,growth,and development,while also being susceptible to hyperglycemia,which is one of the key mechanisms in the development of spermatogenic disorder in type 2 diabetes mellitus(T2DM).This mechanism involves kidney deficiency,which is a common etiology and pathogenesis of both spermatogenesis disorder and T2DM.The kidney storing essence,which encompasses the functions of"dominating reproduction,manufacturing marrow to fill up the brain"bears similarities to the HPG axis.Kidney tonifying therapy can regulate and improve the function of HPG axis,thereby establishing a theoretical basis for the use of kidney tonification therapy in the treatment of spermatogenesis disorder in T2DM.The traditional formula of tonifying the kidney can serve as a complementary treatment for both DM and spermatogenesis disorder.This approach offers a conceptual framework and methodology for the prevention and treatment of T2DM-induced infertility through kidney tonification.
Author 吴松
林连美
卢威
李佳
梁凤霞
杨云松
赵敏
刘琼
AuthorAffiliation 430061 湖北省武汉市,湖北中医药大学中医临床学院;430061 湖北省武汉市,针灸治未病湖北省协同创新中心%430061 湖北省武汉市,湖北中医药大学中医临床学院%430065 湖北省武汉市,湖北中医药大学基础医学院%430061 湖北省武汉市,针灸治未病湖北省协同创新中心;430061 湖北省武汉市,湖北中医药大学针灸骨伤学院
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Author_FL ZHAO Min
YANG Yunsong
LIU Qiong
WU Song
LU Wei
LIANG Fengxia
LI Jia
LIN Lianmei
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DocumentTitle_FL The Idea of Kidney Tonifying Therapy for Spermatogenesis Disorder in Type 2 Diabetes Mellitus Based on the Hypothalamic-pituitary-gonadal Axis
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Issue 33
Keywords Dyszoospermia
Diabetes mellitus,type 2
生精障碍
Reinforcing kidney
糖尿病,2型
Theoretical discussion
补肾
理论探讨
Hypothalamo-hypophyseal system
下丘脑-垂体系统
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430061 湖北省武汉市,湖北中医药大学针灸骨伤学院
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Snippet R322.54%R587.1; 糖尿病(DM)高血糖病理状态是导致男性生精障碍的重要因素之一,下丘脑-垂体-性腺(HPG)轴是人体全身植物性功能、神经内分泌网络的重要枢纽,生理上主导人类生...
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Title 基于下丘脑-垂体-性腺轴探析补肾法治疗2型糖尿病生精障碍的思路
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