以精神障碍为首发症状的抗mGluR5脑炎1例

R749; 本文目的是通过报道一例罕见的以精神障碍为首发症状的抗代谢型谷氨酸受体5(mGluR5)脑炎患者的临床诊疗过程,为临床识别和诊断提供参考.一例38岁的男性患者,以咽痛为前驱症状,记忆力快速下降,伴焦虑抑郁、易激惹及冲动伤人精神运动性兴奋,病程进行性加重,最严重时意识呈浅昏迷状态,认知功能进一步下降,伴幻觉妄想,自知力缺乏,脑脊液和血清抗mGluR5抗体均强阳性(1:100).先后两次使用激素冲击治疗后,患者意识、认知功能、情绪、精神行为等均有改善....

Full description

Saved in:
Bibliographic Details
Published in四川精神卫生 Vol. 35; no. 4; pp. 366 - 369
Main Authors 莫称龙, 赖海岸, 陈贲, 陈俊羽, 崔雅泳, 车鑫, 邹聪, 郑东, 施海姗, 侯乐
Format Journal Article
LanguageChinese
Published 广州医科大学附属脑科医院,广东 广州 510000 2022
Subjects
自身免疫性脑炎
激素免疫
抗mGluR5
边缘性脑炎
霍奇金淋巴瘤
Online AccessGet full text
ISSN1007-3256
DOI10.11886/scjsws20220224001

Cover

Abstract R749; 本文目的是通过报道一例罕见的以精神障碍为首发症状的抗代谢型谷氨酸受体5(mGluR5)脑炎患者的临床诊疗过程,为临床识别和诊断提供参考.一例38岁的男性患者,以咽痛为前驱症状,记忆力快速下降,伴焦虑抑郁、易激惹及冲动伤人精神运动性兴奋,病程进行性加重,最严重时意识呈浅昏迷状态,认知功能进一步下降,伴幻觉妄想,自知力缺乏,脑脊液和血清抗mGluR5抗体均强阳性(1:100).先后两次使用激素冲击治疗后,患者意识、认知功能、情绪、精神行为等均有改善.
AbstractList R749; 本文目的是通过报道一例罕见的以精神障碍为首发症状的抗代谢型谷氨酸受体5(mGluR5)脑炎患者的临床诊疗过程,为临床识别和诊断提供参考.一例38岁的男性患者,以咽痛为前驱症状,记忆力快速下降,伴焦虑抑郁、易激惹及冲动伤人精神运动性兴奋,病程进行性加重,最严重时意识呈浅昏迷状态,认知功能进一步下降,伴幻觉妄想,自知力缺乏,脑脊液和血清抗mGluR5抗体均强阳性(1:100).先后两次使用激素冲击治疗后,患者意识、认知功能、情绪、精神行为等均有改善.
Author 崔雅泳
邹聪
车鑫
陈俊羽
施海姗
赖海岸
陈贲
侯乐
莫称龙
郑东
AuthorAffiliation 广州医科大学附属脑科医院,广东 广州 510000
AuthorAffiliation_xml – name: 广州医科大学附属脑科医院,广东 广州 510000
Author_FL Lai Haian
Cui Yayong
Shi Haishan
Zou Cong
Chen Junyu
Chen Ben
Mo Chenglong
Che Xin
Hou Le
Zheng Dong
Author_FL_xml – sequence: 1
  fullname: Mo Chenglong
– sequence: 2
  fullname: Lai Haian
– sequence: 3
  fullname: Chen Ben
– sequence: 4
  fullname: Chen Junyu
– sequence: 5
  fullname: Cui Yayong
– sequence: 6
  fullname: Che Xin
– sequence: 7
  fullname: Zou Cong
– sequence: 8
  fullname: Zheng Dong
– sequence: 9
  fullname: Shi Haishan
– sequence: 10
  fullname: Hou Le
Author_xml – sequence: 1
  fullname: 莫称龙
– sequence: 2
  fullname: 赖海岸
– sequence: 3
  fullname: 陈贲
– sequence: 4
  fullname: 陈俊羽
– sequence: 5
  fullname: 崔雅泳
– sequence: 6
  fullname: 车鑫
– sequence: 7
  fullname: 邹聪
– sequence: 8
  fullname: 郑东
– sequence: 9
  fullname: 施海姗
– sequence: 10
  fullname: 侯乐
BookMark eNrjYmDJy89LZWCQMjTQMzS0sDDTL07OKi4vNjIwAiETAwNDFgZOQwMDc11jI1MzDgbe4uLMJKCooYGxpaUBJ4PJk91Ln2_a93zpvJez5jxf1Ptkx66Xy6Y97Z_4fHr7865tz2e1POuanuueUxpk-qJl4vOmPsMn-7p5GFjTEnOKU3mhNDdDqJtriLOHro-_u6ezo49usaGBkbFuclJKqrmxcUpKalJionmqmYWFkbGJYZqBmaFxSpqReWJySpKRYUqKaaKBqYlZokWisbmBZZKhqaEp0G3JZmnmxtwM6hBzyxPz0hLz0uOz8kuL8oA2xiP50sTA0NgYAE5RWT8
ClassificationCodes R749
ContentType Journal Article
Copyright Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
Copyright_xml – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
DBID 2B.
4A8
92I
93N
PSX
TCJ
DOI 10.11886/scjsws20220224001
DatabaseName Wanfang Data Journals - Hong Kong
WANFANG Data Centre
Wanfang Data Journals
万方数据期刊 - 香港版
China Online Journals (COJ)
China Online Journals (COJ)
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
DocumentTitle_FL Anti-mGluR5 encephalitis with mental disorders as the initial symptom:a case report
EndPage 369
ExternalDocumentID scjsws202204013
GrantInformation_xml – fundername: (广东省研究生教育创新计划项目); (广东省中医药局科研项目); (广东省医学科学技术研究基金项目); (广东省科技创新战略专项资金; (广州市卫生健康科技项目)
  funderid: (广东省研究生教育创新计划项目); (广东省中医药局科研项目); (广东省医学科学技术研究基金项目); (省基础与应用基础研究基金自然科学基金)面上项目); (广州市卫生健康科技项目)
GroupedDBID -05
2B.
4A8
92F
92I
93N
ABDBF
ABJNI
ACGFS
AFKRA
ALMA_UNASSIGNED_HOLDINGS
BENPR
CCEZO
CCPQU
CIEJG
CW9
GROUPED_DOAJ
PHGZM
PHGZT
PIMPY
PMFND
PSX
PSYQQ
TCJ
TGQ
U1G
U5O
ID FETCH-LOGICAL-s1023-cbde733ddebaa7e6882341f0613df27acdb21dd5a0546a8a3709b1515039c6f73
ISSN 1007-3256
IngestDate Thu May 29 03:55:14 EDT 2025
IsPeerReviewed false
IsScholarly false
Issue 4
Keywords 自身免疫性脑炎
激素免疫
抗mGluR5
边缘性脑炎
霍奇金淋巴瘤
Language Chinese
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-s1023-cbde733ddebaa7e6882341f0613df27acdb21dd5a0546a8a3709b1515039c6f73
PageCount 4
ParticipantIDs wanfang_journals_scjsws202204013
PublicationCentury 2000
PublicationDate 2022
PublicationDateYYYYMMDD 2022-01-01
PublicationDate_xml – year: 2022
  text: 2022
PublicationDecade 2020
PublicationTitle 四川精神卫生
PublicationTitle_FL Sichuan Mental Health
PublicationYear 2022
Publisher 广州医科大学附属脑科医院,广东 广州 510000
Publisher_xml – name: 广州医科大学附属脑科医院,广东 广州 510000
SSID ssib001103990
ssib051370907
ssib036439828
ssj0002912255
Score 1.8829126
Snippet R749; 本文目的是通过报道一例罕见的以精神障碍为首发症状的抗代谢型谷氨酸受体5(mGluR5)脑炎患者的临床诊疗过程,为临床识别和诊断提供参考.一例38岁的男性患者,以咽痛为...
SourceID wanfang
SourceType Aggregation Database
StartPage 366
Title 以精神障碍为首发症状的抗mGluR5脑炎1例
URI https://d.wanfangdata.com.cn/periodical/scjsws202204013
Volume 35
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  issn: 1007-3256
  databaseCode: DOA
  dateStart: 20140101
  customDbUrl:
  isFulltext: true
  dateEnd: 99991231
  titleUrlDefault: https://www.doaj.org/
  omitProxy: true
  ssIdentifier: ssj0002912255
  providerName: Directory of Open Access Journals
– providerCode: PRVPQU
  databaseName: ProQuest Central
  issn: 1007-3256
  databaseCode: BENPR
  dateStart: 20140101
  customDbUrl: http://www.proquest.com/pqcentral?accountid=15518
  isFulltext: true
  dateEnd: 99991231
  titleUrlDefault: https://www.proquest.com/central
  omitProxy: true
  ssIdentifier: ssj0002912255
  providerName: ProQuest
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR3LahRBsEk2Fy-iqPgMe7BPYXSnZ7qn-zi9O2sQDBISyC3MU5FkBXcXIUcJCBGVXAwE8SDED_AgopCvWR3zF1b1dHZHd8EHLENNdXVVddfOVHX1Ywi5yfOAJ75bOIkolONnGXeSBG55yt2sAIeWZZjQv7ciltf9uxt8Y25-q7ZqaThIbqU7M_eV_I9VAQd2xV2y_2DZMVNAAAz2hStYGK5_ZWMa-VRrGnIaBVQzqiME4FYBoKgKqWobDKOyY4gl1SEWhYIqQSNOZZcqF2lUQGWAgAypFgYTUunTSCBGBdt3toarIEgisqoigW3kGr4Rlboe5yJrpfEHgAZenVkqclQr1EYYMB0vMjZSIlsSQr0W6gxVlaqTaG4aIRAAGSgJBMgJCXSBolIaWlCSzSgBdBcbiNpFVHfqWRA2GS0b5gppbXsq7dvY_ZWO2CWchj7CCHSwj60c39RyTa1a_41rWT6GGGzF2jVxxmiqvTStwRI3syY1t4IJYY9VR6if-p3qmBb7fPk1J-IJUYtHvOpTNtOuTsrq65yP-k_72CUmOrOZoV-PEK_R4HB6niwwzF41yIKOVu6vTsJnXBcwmTX1MFqtzapy1wtayqYLMNJhygV3wM2CAtvA031poNztKdXMxrheEfce1GK4tXPkrB18NcPqSTpP5nYeXiD-6OtR-fG4PHp3cvi2fP9y9PnLyYc3317vlwfPy71P5eHu972D6t__Y3e_fPbKHR2_uEjWu9Fae9mx3xJx-ng4iZMmWR54HjjzJI6DXMDAEuK3AqPZrGBBnGYJc-FNFcMQRsQyxpYmGOxDj6SiCLxLpNF73MsvkyaUZ-DmlAt2gsG7L1ketNw0UTkTLPfFFdK0rdy074r-5m8WuPpnkmvkDMJVtu86aQyeDPMbEP8OkkVrtkWTP_oJ3QqA5w
linkProvider ProQuest
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E4%BB%A5%E7%B2%BE%E7%A5%9E%E9%9A%9C%E7%A2%8D%E4%B8%BA%E9%A6%96%E5%8F%91%E7%97%87%E7%8A%B6%E7%9A%84%E6%8A%97mGluR5%E8%84%91%E7%82%8E1%E4%BE%8B&rft.jtitle=%E5%9B%9B%E5%B7%9D%E7%B2%BE%E7%A5%9E%E5%8D%AB%E7%94%9F&rft.au=%E8%8E%AB%E7%A7%B0%E9%BE%99&rft.au=%E8%B5%96%E6%B5%B7%E5%B2%B8&rft.au=%E9%99%88%E8%B4%B2&rft.au=%E9%99%88%E4%BF%8A%E7%BE%BD&rft.date=2022&rft.pub=%E5%B9%BF%E5%B7%9E%E5%8C%BB%E7%A7%91%E5%A4%A7%E5%AD%A6%E9%99%84%E5%B1%9E%E8%84%91%E7%A7%91%E5%8C%BB%E9%99%A2%2C%E5%B9%BF%E4%B8%9C+%E5%B9%BF%E5%B7%9E+510000&rft.issn=1007-3256&rft.volume=35&rft.issue=4&rft.spage=366&rft.epage=369&rft_id=info:doi/10.11886%2Fscjsws20220224001&rft.externalDocID=scjsws202204013
thumbnail_s http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fscjsws%2Fscjsws.jpg