胞外体来源的非编码RNA在颅脑创伤中的作用

颅脑创伤是世界范围内死亡和致残的主要原因,给公共健康带来了巨大的威胁,但目前的诊断和治疗手段十分有限.胞外体是介导细胞间通信和物质转运的微囊泡,其中包含了丰富的非编码RNA.它们参与颅脑创伤后的病理生理反应过程,但具体的作用机制仍不明确.作为胞外体内容物的重要组成部分,非编码RNA对研究颅脑创伤的诊断、精准治疗、疗效评估、预后预测及并发症的防治等均具有重要意义....

Full description

Saved in:
Bibliographic Details
Published in中南大学学报（医学版） Vol. 46; no. 2; pp. 183 - 188
Main Authors 吴昀, 刘劲芳
Format Journal Article
LanguageChinese
Published 中南大学湘雅医院神经外科,长沙410008 28.02.2021
Subjects
胞外体
非编码RNA
颅脑创伤
Online AccessGet full text
ISSN1672-7347
DOI10.11817/j.issn.1672-7347.2021.190702

Cover

Abstract 颅脑创伤是世界范围内死亡和致残的主要原因,给公共健康带来了巨大的威胁,但目前的诊断和治疗手段十分有限.胞外体是介导细胞间通信和物质转运的微囊泡,其中包含了丰富的非编码RNA.它们参与颅脑创伤后的病理生理反应过程,但具体的作用机制仍不明确.作为胞外体内容物的重要组成部分,非编码RNA对研究颅脑创伤的诊断、精准治疗、疗效评估、预后预测及并发症的防治等均具有重要意义.
AbstractList 颅脑创伤是世界范围内死亡和致残的主要原因,给公共健康带来了巨大的威胁,但目前的诊断和治疗手段十分有限.胞外体是介导细胞间通信和物质转运的微囊泡,其中包含了丰富的非编码RNA.它们参与颅脑创伤后的病理生理反应过程,但具体的作用机制仍不明确.作为胞外体内容物的重要组成部分,非编码RNA对研究颅脑创伤的诊断、精准治疗、疗效评估、预后预测及并发症的防治等均具有重要意义.
Author 吴昀
刘劲芳
AuthorAffiliation 中南大学湘雅医院神经外科,长沙410008
AuthorAffiliation_xml – name: 中南大学湘雅医院神经外科,长沙410008
Author_FL WU Yun
LIU Jinfang
Author_FL_xml – sequence: 1
  fullname: WU Yun
– sequence: 2
  fullname: LIU Jinfang
Author_xml – sequence: 1
  fullname: 吴昀
– sequence: 2
  fullname: 刘劲芳
BookMark eNo9T09LAkEcnYNBZn6M6LTb_GZ2d2aOIv0DKYg6y-zsTGkxQkNUx8igo1F4KJUIAy_dI_TbrK5-izaKTu_xeLw_K6hgW1YjtAbYB-DANpp-wznrQ8SIx2jAfIIJ-CAww6SAiv_6Mio714gxFkLQiLMiEvPbwXTYTSePs_777KuTPbcX_UE27mavNwd7lWlvtHi7m7cfpvcv6XiYfn7khnTSy55Gq2jJyDOny39YQkdbm4fVHa-2v71brdQ8B_kID0KltDI8DiEhigdKKklZQBRjEZeKYMM11orj0EgOgREx06BzogJNI5LQElr_zb2U1kh7XG-2Ls5t3lg_sdenydXPVUwwAP0Gjw5g_w
ContentType Journal Article
Copyright Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
Copyright_xml – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
DBID 2B.
4A8
92I
93N
PSX
TCJ
DOI 10.11817/j.issn.1672-7347.2021.190702
DatabaseName Wanfang Data Journals - Hong Kong
WANFANG Data Centre
Wanfang Data Journals
万方数据期刊 - 香港版
China Online Journals (COJ)
China Online Journals (COJ)
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
DocumentTitle_FL Effect of exosome-derived non-coding RNA on traumatic brain injury
EndPage 188
ExternalDocumentID hnykdx202102011
GrantInformation_xml – fundername: 湖南省自然科学基金
  funderid: (2018JJ2649)
GroupedDBID 2B.
4A8
92I
93N
ALMA_UNASSIGNED_HOLDINGS
PSX
RPM
TCJ
ID FETCH-LOGICAL-s1021-15ccecf8b51d2c84caca3742c7768ac20f8e0ec805fa814f9b7e1e14fc4e362d3
ISSN 1672-7347
IngestDate Thu May 29 03:55:50 EDT 2025
IsPeerReviewed false
IsScholarly true
Issue 2
Keywords 胞外体
非编码RNA
颅脑创伤
Language Chinese
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-s1021-15ccecf8b51d2c84caca3742c7768ac20f8e0ec805fa814f9b7e1e14fc4e362d3
PageCount 6
ParticipantIDs wanfang_journals_hnykdx202102011
PublicationCentury 2000
PublicationDate 2021-02-28
PublicationDateYYYYMMDD 2021-02-28
PublicationDate_xml – month: 02
  year: 2021
  text: 2021-02-28
  day: 28
PublicationDecade 2020
PublicationTitle 中南大学学报（医学版）
PublicationTitle_FL Journal of Central South University(Medical Science)
PublicationYear 2021
Publisher 中南大学湘雅医院神经外科,长沙410008
Publisher_xml – name: 中南大学湘雅医院神经外科,长沙410008
SSID ssib009993687
ssib006709132
ssib051368348
ssib006563246
ssib008143990
ssib002039679
ssib006576295
ssj0002511111
ssib001050736
ssib006703077
ssib001186800
ssib001427679
ssib002262845
Score 2.2942243
Snippet 颅脑创伤是世界范围内死亡和致残的主要原因,给公共健康带来了巨大的威胁,但目前的诊断和治疗手段十分有限.胞外体是介导细胞间通信和物质转运的微囊泡,其中包含了丰富的非...
SourceID wanfang
SourceType Aggregation Database
StartPage 183
Title 胞外体来源的非编码RNA在颅脑创伤中的作用
URI https://d.wanfangdata.com.cn/periodical/hnykdx202102011
Volume 46
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAQN
  databaseName: PubMed Central
  issn: 1672-7347
  databaseCode: RPM
  dateStart: 20210101
  customDbUrl:
  isFulltext: true
  dateEnd: 99991231
  titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/
  omitProxy: true
  ssIdentifier: ssj0002511111
  providerName: National Library of Medicine
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR1Na9VAMNQK4kUUFb_pwTm-Z3aT7McxSfMogj1IC72VfLYqvIJtQXsTK3hUlB60LSIVevEu0v6b9_raf-HMJn1vraLVS5jdnZ3ZndlkZjb74Th3OStYgXapFWQeBiipz1pZRisAXC8VSvKCmfmOB9Niata_PxfMjZ1ZsFYtra5k7Xztt_tK_kermId6pV2y_6DZIVHMQBj1i0_UMD5PpWNIFCgPdAJJAKEPWkDiQzQJ2oNEgJ6EMCAgCkG7kEjQISgfEk1FVEtCFJtaEkIXncqH0yGR0jGEitBCDiowXJA4oyKlQEeGS0wcCVAQTlrE6wbEJsdHOrb7a-EjKUSTTcvDGsAGCwsQoELThQ6xQ9ZUK4YosnAkKG2KapzhvIbphwuRbySBPXDtEupGTS6EiJseIuDZcyCcWXvKadServEobW1oaxIUSW_YZswxIiVpB8fyR5yOpT5J1FDUPDb4AUQdQ5NjXZ_-kthmREiMW7z6LNFjO9NMtT6ywv3aaLD6Kp_G_2D1NYe_mjZlDsR6bDi0hxzaJI82unXS5SObPlxpudh9_qR4xk1k79Ie-LNcCsFPTGuhk42fevscQSWUdW4j87GW9TuXu57-Kc0Fujkjw4BBAjrqwkqjzbU2gAtzDJ2005pZG5wVozB5xB-jGE-M4oiAYcpr4nhyuShOZuau7aFczjlwLLV7f5KZ2azXrdLuguVXzlx0LjQB4URYv92XnLG1xcuOPny53d_Z6O2_O9j6cvD9zeDD-tHW9mBvY_DpBb6j_c3do8-vDtff9l9_7O3t9L59RYTe_ubg_e4VZ7aTzMRTreaSk9Yyo5HMgjwv80plASt4rvw8zVNP-jyXUig6P7VSpVvmyg2qFMVS6UyWrEQg90t0PgvvqjPeXeqW15wJEVQiLTCT7jRIK09VoqpkpVWpC1cXwXVnounqfPMRW54_MT5u_B3lpnN-9ArecsZXnq6Wt9ExX8numEH1A3cfoaE
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%83%9E%E5%A4%96%E4%BD%93%E6%9D%A5%E6%BA%90%E7%9A%84%E9%9D%9E%E7%BC%96%E7%A0%81RNA%E5%9C%A8%E9%A2%85%E8%84%91%E5%88%9B%E4%BC%A4%E4%B8%AD%E7%9A%84%E4%BD%9C%E7%94%A8&rft.jtitle=%E4%B8%AD%E5%8D%97%E5%A4%A7%E5%AD%A6%E5%AD%A6%E6%8A%A5%EF%BC%88%E5%8C%BB%E5%AD%A6%E7%89%88%EF%BC%89&rft.au=%E5%90%B4%E6%98%80&rft.au=%E5%88%98%E5%8A%B2%E8%8A%B3&rft.date=2021-02-28&rft.pub=%E4%B8%AD%E5%8D%97%E5%A4%A7%E5%AD%A6%E6%B9%98%E9%9B%85%E5%8C%BB%E9%99%A2%E7%A5%9E%E7%BB%8F%E5%A4%96%E7%A7%91%2C%E9%95%BF%E6%B2%99410008&rft.issn=1672-7347&rft.volume=46&rft.issue=2&rft.spage=183&rft.epage=188&rft_id=info:doi/10.11817%2Fj.issn.1672-7347.2021.190702&rft.externalDocID=hnykdx202102011
thumbnail_s http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fhnykdx%2Fhnykdx.jpg