肝脏Mboat7的缺乏与肝纤维化有关
<正>位于膜结合O-酰基转移酶结构域7 (MBOAT7) 基因的rs641738c>T变异与肝脏疾病,如非酒精性脂肪性肝病 (NAFLD) 、酒精相关性肝病、乙型和丙型肝炎等纤维化相关。该研究旨在了解rs641738c>T的变异在NAFLD发病机理机制中所发挥的作用。来自德国德累斯顿大学医院的Thangapandi等制作了具有肝细胞特异性缺失MBOAT7 (Mboat7Δhep)的小鼠,并通...
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Published in | Linchuang gandanbing zazhi Vol. 36; no. 8; p. 1895 |
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Main Authors | , , , , |
Format | Journal Article |
Language | Chinese |
Published |
Changchun
Journal of Clinical Hepatology
01.01.2020
吉林大学第一医院感染病中心肝病科 |
Online Access | Get full text |
ISSN | 1001-5256 2097-3497 |
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Abstract | <正>位于膜结合O-酰基转移酶结构域7 (MBOAT7) 基因的rs641738c>T变异与肝脏疾病,如非酒精性脂肪性肝病 (NAFLD) 、酒精相关性肝病、乙型和丙型肝炎等纤维化相关。该研究旨在了解rs641738c>T的变异在NAFLD发病机理机制中所发挥的作用。来自德国德累斯顿大学医院的Thangapandi等制作了具有肝细胞特异性缺失MBOAT7 (Mboat7Δhep)的小鼠,并通 |
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AbstractList | <正>位于膜结合O-酰基转移酶结构域7 (MBOAT7) 基因的rs641738c>T变异与肝脏疾病,如非酒精性脂肪性肝病 (NAFLD) 、酒精相关性肝病、乙型和丙型肝炎等纤维化相关。该研究旨在了解rs641738c>T的变异在NAFLD发病机理机制中所发挥的作用。来自德国德累斯顿大学医院的Thangapandi等制作了具有肝细胞特异性缺失MBOAT7 (Mboat7Δhep)的小鼠,并通 |
Author | 马仁舒 KNITTELFELDER, O 辛桂杰 THANGAPANDI, V R Brosch, M |
AuthorAffiliation | 吉林大学第一医院感染病中心肝病科 |
AuthorAffiliation_xml | – name: 吉林大学第一医院感染病中心肝病科 |
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Snippet | <正>位于膜结合O-酰基转移酶结构域7 (MBOAT7) 基因的rs641738c>T变异与肝脏疾病,如非酒精性脂肪性肝病 (NAFLD) 、酒精相关性肝病、乙型和丙型肝炎等纤维化相关。该研究旨在了... |
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Title | 肝脏Mboat7的缺乏与肝纤维化有关 |
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