Primary malignant cutaneous lymphomas excluding mycosis fungoides. Anatomoclinical study of 16 cases
Cutaneous primary lymphomas excluding mycosis fungoides and Sezary Syndrome represent a rare condition. Few papers are published on the subject. The authors report a retrospective study of 16 cases concerning only these primary lymphomas. It comprises 10 adults and 6 children. In 13 cases the cutane...
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Published in | Annales de pathologie Vol. 4; no. 4; p. 273 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | French |
Published |
France
01.09.1984
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ISSN | 0242-6498 |
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Abstract | Cutaneous primary lymphomas excluding mycosis fungoides and Sezary Syndrome represent a rare condition. Few papers are published on the subject. The authors report a retrospective study of 16 cases concerning only these primary lymphomas. It comprises 10 adults and 6 children. In 13 cases the cutaneous tumor was solitary without extra-cutaneous lesion, in 3 cases there was a satellite simultaneous lymph node. The most frequent location was head and neck region (7 cases with 4 cases from children); limbs were concerned too (5 cases/16); more rarely trunk. Our cases were classified with reference to lennert's classification. We found that large cells lymphomas were predominant: centroblastic (4 cases), lymphoblastic (4 cases), immunoblastic lymphomas (6 cases). The clinical course was unfavourable in 50% of our cases in less than 3 years: 6 lethal cases, and 2 metastatic disseminations. These 8 cases belonged to the pejorative group of lymphomas (large cells type). The 2 cases with small cells population (centrocyto-centroblastic and lymphoplasmocytoïd type) were free of disease for 5 and 2 years after diagnosis. Thus, our experience suggests that there is a relations hip between the histologic type of cutaneous lymphoma and the course of the disease. In disseminated cases, the extra-cutaneous extension was located in lymph nodes, bone marrow, as it was mentioned in literature. |
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AbstractList | Cutaneous primary lymphomas excluding mycosis fungoides and Sezary Syndrome represent a rare condition. Few papers are published on the subject. The authors report a retrospective study of 16 cases concerning only these primary lymphomas. It comprises 10 adults and 6 children. In 13 cases the cutaneous tumor was solitary without extra-cutaneous lesion, in 3 cases there was a satellite simultaneous lymph node. The most frequent location was head and neck region (7 cases with 4 cases from children); limbs were concerned too (5 cases/16); more rarely trunk. Our cases were classified with reference to lennert's classification. We found that large cells lymphomas were predominant: centroblastic (4 cases), lymphoblastic (4 cases), immunoblastic lymphomas (6 cases). The clinical course was unfavourable in 50% of our cases in less than 3 years: 6 lethal cases, and 2 metastatic disseminations. These 8 cases belonged to the pejorative group of lymphomas (large cells type). The 2 cases with small cells population (centrocyto-centroblastic and lymphoplasmocytoïd type) were free of disease for 5 and 2 years after diagnosis. Thus, our experience suggests that there is a relations hip between the histologic type of cutaneous lymphoma and the course of the disease. In disseminated cases, the extra-cutaneous extension was located in lymph nodes, bone marrow, as it was mentioned in literature. |
Author | Wechsler, J Caillaud, J M Clerici, T Pinaudeau, Y Micheau, C Ghozali, F |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/6508884$$D View this record in MEDLINE/PubMed |
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DocumentTitleAlternate | Lymphomes malins cutanés primitifs en dehors du mycosis fongoïde. Etude anatomo-clinique de 16 cas |
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Snippet | Cutaneous primary lymphomas excluding mycosis fungoides and Sezary Syndrome represent a rare condition. Few papers are published on the subject. The authors... |
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SubjectTerms | Adult Aged Child Child, Preschool Female Humans Infant Lymphoma - classification Lymphoma - mortality Lymphoma - pathology Male Middle Aged Neoplasm Metastasis Prognosis Retrospective Studies Skin Neoplasms - classification Skin Neoplasms - mortality Skin Neoplasms - pathology |
Title | Primary malignant cutaneous lymphomas excluding mycosis fungoides. Anatomoclinical study of 16 cases |
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