Kinetic modeling of [18F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non‐human primate brain - Jin, Hongjun; Yue, Xuyi; Liu, Hui; Han, Junbin; Flores, Hubert; Su, Yi; Parsons, Stanley M.; Perlmutter, Joel S.; Tu, Zhude (Journal of neurochemistry, 2018)
Keywords: [18F]VAT; Acetylcholine; Alzheimer's disease; Animal models; Animals; binding potential; Biomarkers; Brain; Brain - diagnostic imaging; Brain - metabolism; Cerebellum; Emission analysis; Fluorine isotopes; Fluorine Radioisotopes - pharmacokinetics; Hemispheres; Kinetics; Linear analysis; Macaca fascicularis; Male; Medical imaging; Medical treatment; Modelling; Models, Neurological; Neurodegenerative diseases; Neuroimaging; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Radiopharmaceuticals - pharmacokinetics; Reproducibility; Reproducibility of Results; Tomography; tracer kinetic modeling; Vesicular Acetylcholine Transport Proteins - metabolism; Vesicular acetylcholine transporter; [18F]VAT; positron emission tomography; vesicular acetylcholine transporter; binding potential; tracer kinetic modeling