Modified Citrus Pectin / Alginate Dietary Supplement Increased Fecal Excretion of Uranium: A Family

• Published in: Alternative therapies in health and medicine Vol. 25; no. 4; pp. 20 - 24
• Main Authors: Eliaz, Isaac, Weil, Elaine, Schwarzbach, Jamie, Wilk, Barry
• Format: Journal Article
• Language: English
• Published: United States InnoVision Health Media, Inc 01.07.2019
• Subjects: Agricultural management; Alginates - administration & dosage; Aqueous solutions; Case reports; Citrus fruits; Dietary Supplements; Environmental health; Feces; Female; Food; Heavy Metal Poisoning - prevention & control; Heavy metals; Humans; Lead; Lead content; Lung cancer; Male; Mining; Molecular weight; Pectins - administration & dosage; Treatment Outcome; Uranium; Uranium - toxicity; Uranium - urine; Urine; United States > US
• ISSN: 1078-6791

Uranium is found in geological deposits around the world. Toxicology of uranium includes nephrotoxicity, carcinogenicity, genotoxicity, diminished bone growth, and developmental defects. Mining and agricultural practices have escalated the regional exposure. A family of six living in the Phoenix, AZ area had concerns about uranium exposure. For intervention, a dietary supplement of modified citrus pectin: sodium alginate (2:1) was recommended based on research supporting abilities to lower heavy metal toxicity. Baseline urine and fecal samples were analyzed using inductively coupled plasma mass spectrometry. The supplement was self-administered at 3 capsules (750 mg/capsule) twice daily. Samples were taken at baseline, 6-days, and 6-weeks, additional fecal samples before stopping supplement and then after a 6-week washout period. Home water system was tested as well for heavy metals. Urine showed no detectable uranium whereas feces had significant change at 6-days, which persisted at 6-weeks. After a post-treatment period of 6-weeks, a decrease in excretion was seen in 5 of the 6 subjects. Home water showed cautionary levels of uranium. The supplement promoted fecal excretion of what is likely ongoing low-level exposure via ingestion. This is the first report of a supplement promoting uranium excretion suggesting it may reduce negative health effects in regions where chronic uranium exposure is known.